Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22664528 | 1.00 | TDP1 (0.51) | TDP1ALDH1A1CYP1A2CYP2C9MAPK1 | |
| SCHEMBL22664519 | 0.85 | MAPT (0.58) | TDP1ALDH1A1MAPK1HTTGAA | |
| SCHEMBL22664518 | 0.85 | MAPT (0.58) | TDP1ALDH1A1MAPK1HTTGAA | |
| SCHEMBL22664536 | 0.82 | HDAC3 (0.56) | TDP1ALDH1A1CYP1A2CYP2C9HTT | |
| SCHEMBL22664537 | 0.82 | HDAC3 (0.56) | TDP1ALDH1A1CYP1A2CYP2C9HTT | |
| SCHEMBL22692996 | 0.81 | MAPT (0.62) | TDP1ALDH1A1MAPK1HPGDHTT | |
| SCHEMBL22645438 | 0.81 | ALDH1A1 (0.54) | ALDH1A1CYP2C9CYP3A4CYP2C19HPGD | |
| SCHEMBL22645433 | 0.81 | ALDH1A1 (0.54) | ALDH1A1CYP2C9CYP3A4CYP2C19HPGD | |
| SCHEMBL22645435 | 0.81 | ALDH1A1 (0.54) | ALDH1A1CYP2C9CYP3A4CYP2C19HPGD | |
| SCHEMBL22645440 | 0.81 | ALDH1A1 (0.54) | ALDH1A1CYP2C9CYP3A4CYP2C19HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10842795-B1 | Chemosensitization of resistant Pseudomonas aeruginosa by synthetically related compounds | KING ABDULAZIZ UNIVERSITY (SA) | 2020-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10842795-B1 | Chemosensitization of resistant Pseudomonas aeruginosa by synthetically related compounds | ABCC1, SLC11A2, ABCB1 | TDP1 4612/4885ALDH1A1 3989/4885CYP1A2 4154/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.