Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.71 |
| ▸ | MAPT | P10636 | 1/20 | 0.71 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | MASP2 | O00187 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.36 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30900484 | 1.00 | GAA (0.71) | GAAMAPTSMYD3BRD4CREBBP | |
| SCHEMBL10742930 | 1.00 | GAA (0.71) | GAAMAPTSMYD3BRD4CREBBP | |
| Hydrochloric Acid SCHEMBL28262901 | 0.98 | GAA (0.69) | GAAMAPTSMYD3BRD4CREBBP | |
| Indole SCHEMBL11289138 | 0.87 | MAPT (0.55) | GAAMAPTSMYD3MTNR1AMTNR1B | |
| SCHEMBL27556878 | 0.85 | GAA (0.76) | GAAMAPTSMYD3BRD4CREBBP | |
| SCHEMBL91080 | 0.83 | GAA (1.00) | GAAMAPTSMYD3BRD4CREBBP | |
| SCHEMBL14003020 | 0.83 | GAA (1.00) | GAAMAPTSMYD3BRD4CREBBP | |
| SCHEMBL29365197 | 0.83 | GAA (1.00) | GAAMAPTSMYD3BRD4CREBBP | |
| SCHEMBL1134239 | 0.83 | GAA (1.00) | GAAMAPTSMYD3BRD4CREBBP | |
| SCHEMBL29495388 | 0.83 | GAA (1.00) | GAAMAPTSMYD3BRD4CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4486444-A1 | 3-ALKYNYL CARBOXAMIDES AS AEP MODULATORS | F. Hoffmann-La Roche AG (CH) | 2025-01-08 | — | — | EP | claimed |
| CN-117794896-A | Protease inhibitors for the treatment of coronavirus infections | 斯克里普斯研究学院 | 2024-03-29 | — | — | CN | claimed |
| WO-2023165943-A1 | 3-ALKYNYL CARBOXAMIDES AS AEP MODULATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-09-07 | — | — | WO | claimed |
| WO-2026098560-A2 | BENZENE-CONTAINING POLYCYCLIC DERIVATIVE MODULATOR, PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翰森生物医药科技有限公司 | 2026-05-15 | — | — | WO | disclosed |
| EP-4486444-A1 | 3-ALKYNYL CARBOXAMIDES AS AEP MODULATORS | F. Hoffmann-La Roche AG (CH) | 2025-01-08 | — | — | EP | disclosed |
| CN-117794896-A | Protease inhibitors for the treatment of coronavirus infections | 斯克里普斯研究学院 | 2024-03-29 | — | — | CN | disclosed |
| WO-2023165943-A1 | 3-ALKYNYL CARBOXAMIDES AS AEP MODULATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-09-07 | — | — | WO | disclosed |
| WO-2022133588-A1 | RNA VIRUS INHIBITOR COMPOUNDS AND USES THEREOF | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2022-06-30 | — | — | WO | disclosed |
| EP-3704090-A1 | MODULATORS OF THE INTEGRATED STRESS PATHWAY | Calico Life Sciences LLC (US) | 2020-09-09 | — | — | EP | disclosed |
| CN-109906221-A | N- alkyl sulphonyl sulfonylindoline compounds and salt, garderning pesticide and its application method containing the compound | 日本农药株式会社 | 2019-06-18 | — | — | CN | disclosed |
| WO-2017035352-A1 | CARBAMATE, ESTER, AND KETONE COMPOUNDS FOR TREATMENT OF MEDICAL DISORDERS | ACHILLION PHARMACEUTICALS, INC. (US) | 2017-03-02 | — | — | WO | disclosed |
| WO-1993008188-A1 | TRICYCLIC QUINOXALINEDIONES AS GLUTAMATE RECEPTOR ANTAGONISTS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1993-04-29 | — | — | WO | disclosed |
| US-4785118-A | Process for preparing indoline-2-carboxylic acids via alpha-hydroxy-2-nitrobenzenepropanoic acid | AMERICAN HOME PRODUCTS CORPORATION (US) | 1988-11-15 | — | — | US | disclosed |
| US-4727183-A | Process for the asymmetric synthesis of chiral α-hydroxy-2-nitrobenzenepropanoic acid | AMERICAN HOME PRODUCTS CORPORATION (US) | 1988-02-23 | — | — | US | disclosed |
| US-4645857-A | Process for preparing indoline-2-carboxylic acids via α-hydroxy-2-nitrobenzenepropanoic acid | AMERICAN HOME PRODUCTS CORPORATION (US) | 1987-02-24 | — | — | US | disclosed |
| US-4644081-A | Process for the asymmetric synthesis of chiral indoline-2-carboxylic acids | AMERICAN HOME PRODUCTS CORPORATION (US) | 1987-02-17 | — | — | US | disclosed |
| US-4614806-A | Process for the asymmetric synthesis of chiral indoline-2-carboxylic acids | AMERICAN HOME PRODUCTS CORPORATION (US) | 1986-09-30 | — | — | US | disclosed |
| US-4585879-A | Process for preparing indoline-2-carboxylic acids via alpha-hydroxy-2-nitrobenzenepropanoic acid | AMERICAN HOME PRODUCTS CORPORATION (US) | 1986-04-29 | — | — | US | disclosed |
| US-4535168-A | Preparation of indoline-2-carboxylic acid via the intermediate indoline-2-carboxylic acid ester tin complex | AMERICAN HOME PRODUCTS CORPORATION (US) | 1985-08-13 | — | — | US | disclosed |
| US-4485241-A | Reduction of indole-2-carboxylic acids to indoline-2-carboxylic acids with lithium, sodium, or potassium in ammonia | AMERICAN HOME PRODUCTS CORPORATION (US) | 1984-11-27 | — | — | US | disclosed |