Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.47 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.47 |
| ▸ | ITGAL | P20701 | 1/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
| ▸ | CA6 | P23280 | 1/20 | 0.47 |
| ▸ | AHR | P35869 | 1/20 | 0.47 |
| ▸ | ADK | P55263 | 1/20 | 0.47 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.35 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10742930 | 0.87 | GAA (0.71) | MAPTGAAARSMYD3MTNR1A | |
| SCHEMBL30900484 | 0.87 | GAA (0.71) | MAPTGAAARSMYD3MTNR1A | |
| SCHEMBL2266601 | 0.87 | GAA (0.71) | MAPTGAAARSMYD3MTNR1A | |
| Hydrochloric Acid SCHEMBL28262901 | 0.85 | GAA (0.69) | MAPTGAAARSMYD3MTNR1A | |
| Indole SCHEMBL27631042 | 0.77 | TRPA1 (0.74) | MAPTGAATRPA1CA1CA2 | |
| Indole SCHEMBL5205084 | 0.77 | TRPA1 (0.74) | MAPTGAATRPA1CA1CA2 | |
| Indole SCHEMBL384964 | 0.75 | TRPA1 (0.71) | MAPTGAATRPA1CA1CA2 | |
| Indole SCHEMBL29160563 | 0.75 | TRPA1 (0.71) | MAPTGAATRPA1CA1CA2 | |
| Indole SCHEMBL3720161 | 0.74 | TRPA1 (0.59) | MAPTTRPA1CA1CA2ITGB2 | |
| Indole SCHEMBL712897 | 0.73 | TRPA1 (0.68) | MAPTGAATRPA1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0055603-A1 | Indole-dihydroindole alkaloid derivatives | ELI LILLY AND COMPANY (US) | 1982-07-07 | — | — | EP | disclosed |
| US-4203898-A | ANTICARCINOGENIC | ELI LILLY AND COMPANY (US) | 1980-05-20 | — | — | US | disclosed |