Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17437817 | 0.83 | MEN1 (0.46) | ALDH1A1TDP1TSHRMEN1KMT2A | |
| Propylene Oxide SCHEMBL27795211 | 0.81 | ALDH1A1 (0.52) | ALDH1A1TDP1TSHRMEN1KMT2A | |
| SCHEMBL2011660 | 0.79 | ALDH1A1 (0.37) | ALDH1A1TDP1TSHRHIF1A | |
| SCHEMBL29571004 | 0.78 | ALDH1A1 (0.50) | ALDH1A1TDP1MEN1KMT2AMAPT | |
| SCHEMBL7721987 | 0.77 | TSHR (0.47) | ALDH1A1TDP1TSHRMEN1KMT2A | |
| SCHEMBL584830 | 0.76 | ALDH1A1 (0.71) | ALDH1A1TDP1TSHRMEN1KMT2A | |
| SCHEMBL29613273 | 0.76 | ALDH1A1 (0.71) | ALDH1A1TDP1TSHRMEN1KMT2A | |
| Orthocresol SCHEMBL1066364 | 0.75 | ALDH1A1 (0.43) | ALDH1A1TDP1MEN1KMT2AMAPT | |
| SCHEMBL11427022 | 0.75 | MEN1 (0.55) | ALDH1A1TDP1TSHRMEN1KMT2A | |
| Orthocresol SCHEMBL5691892 | 0.74 | CYP1A2 (0.44) | ALDH1A1TDP1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9296011-B2 | Prosthesis having varied concentration of beneficial agent | ABBOTT LABORATORIES (US) | 2016-03-29 | — | — | US | disclosed |
| CN-203280431-U | Three-constituent mixing device and three-constituent mixing binding agent set | MITSU CHEMICALS INC | 2013-11-13 | — | — | CN | disclosed |
| US-20110262621-A1 | METHOD OF LOADING BENEFICIAL AGENT ON A PROSTHESIS | ABBOTT LABORATORES | 2011-10-27 | — | — | US | disclosed |
| US-8001926-B2 | System and method of loading and detecting beneficial agent on a prosthesis | ABBOTT LABORATORIES (US) | 2011-08-23 | — | — | US | disclosed |
| EP-2198976-A2 | Method of loading beneficial agent to a prosthesis by fluid-jet application | Abbott Laboratories (US) | 2010-06-23 | — | — | EP | disclosed |
| EP-1562517-B1 | PROSTHESIS WITH MULTIPLE DRUGS IN DISCRETE UNMIXED DROPLETS | ABBOTT LAB (US) | 2010-06-16 | — | — | EP | disclosed |
| EP-1572029-B1 | METHOD OF LOADING BENEFICIAL AGENT TO A PROSTHESIS BY FLUID-JET APPLICATION | ABBOTT LAB (US) | 2010-03-24 | — | — | EP | disclosed |
| US-7645476-B2 | Method of loading beneficial agent to a prosthesis by fluid-jet application | ABBOTT LABORATORIES (US) | 2010-01-12 | — | — | US | disclosed |
| US-20100003396-A1 | System and Method of Loading and Detecting Beneficial Agent on a Prosthesis | ABBOTT LABORATORIES | 2010-01-07 | — | — | US | disclosed |
| US-7597764-B2 | System of loading beneficial agent to a prosthesis by fluid-jet | ABBOTT LABORATORIES (US) | 2009-10-06 | — | — | US | disclosed |
| US-20070053953-A1 | Method of loading beneficial agent to a prosthesis by fluid-jet application | VERLEE DONALD | 2007-03-08 | — | — | US | disclosed |
| EP-1572029-A1 | METHOD OF LOADING BENEFICIAL AGENT TO A PROSTHESIS BY FLUID-JET APPLICATION | Abbott Laboratories (US) | 2005-09-14 | — | — | EP | disclosed |
| EP-1562517-A1 | PROSTHESIS WITH MULTIPLE DRUGS IN DISCRETE UNMIXED DROPLETS | Abbott Laboratories (US) | 2005-08-17 | — | — | EP | disclosed |
| EP-1562518-A1 | PROSTHESIS HAVING VARIED CONCENTRATION OF BENEFICIAL AGENT | Abbott Laboratories (US) | 2005-08-17 | — | — | EP | disclosed |
| US-20040254634-A1 | Prosthesis having varied concentration of beneficial agent | ABBOTT LABORATORIES | 2004-12-16 | — | — | US | disclosed |
| US-20040202773-A1 | Method of loading beneficial agent to a prosthesis by fluid-jet application | ABBOTT LABORATORIES | 2004-10-14 | — | — | US | disclosed |
| US-20040185081-A1 | Prosthesis with multiple drugs applied separately by fluid jet application in discrete unmixed droplets | ABBOTT LABORATORIES | 2004-09-23 | — | — | US | disclosed |
| WO-2004043300-A1 | PROSTHESIS WITH MULTIPLE DRUGS IN DISCRETE UNMIXED DROPLETS | ABBOTT LABORATORIES (US) | 2004-05-27 | — | — | WO | disclosed |
| WO-2004043298-A1 | PROSTHESIS HAVING VARIED CONCENTRATION OF BENEFICIAL AGENT | ABBOTT LABORATORIES (US) | 2004-05-27 | — | — | WO | disclosed |
| WO-2004043299-A1 | METHOD OF LOADING BENEFICIAL AGENT TO A PROSTHESIS BY FLUID-JET APPLICATION | ABBOTT LABORATORIES (US) | 2004-05-27 | — | — | WO | disclosed |