Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 6/20 | 0.46 |
| ▸ | BCHE | P06276 | 3/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.40 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.37 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15239057 | 0.88 | FFAR1 (0.57) | FFAR1FFAR4 | |
| SCHEMBL10267355 | 0.88 | FFAR1 (0.57) | FFAR1FFAR4 | |
| SCHEMBL22668554 | 0.85 | FFAR1 (0.62) | FFAR1BCHEFFAR4PLA2G4BLTA4H | |
| SCHEMBL10267354 | 0.80 | FFAR1 (0.60) | FFAR1PLA2G4BALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL15239360 | 0.80 | FFAR1 (0.60) | FFAR1PLA2G4BALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL15239382 | 0.80 | FFAR1 (0.60) | FFAR1PLA2G4BALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL2772725 | 0.75 | FFAR1 (0.61) | FFAR1BCHEFFAR4LTA4HEPHX2 | |
| SCHEMBL10259737 | 0.75 | FFAR1 (0.67) | FFAR1FFAR4PPARGPPARA | |
| SCHEMBL15239252 | 0.75 | FFAR1 (0.67) | FFAR1FFAR4PPARGPPARA | |
| SCHEMBL22668047 | 0.74 | FFAR1 (0.52) | FFAR1BCHEFFAR4PLA2G4BLTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2595952-B1 | AGONISTS OF GPR40 | CONNEXIOS LIFE SCIENCES PVT LTD (IN) | 2020-11-18 | — | — | EP | disclosed |