Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 7/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.43 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10267410 | 0.86 | FFAR1 (0.65) | FFAR1ALDH1A1SMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL15238969 | 0.86 | FFAR1 (0.65) | FFAR1ALDH1A1SMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL22668029 | 0.86 | FFAR1 (0.64) | FFAR1ALDH1A1SMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL22668261 | 0.86 | FFAR1 (0.64) | FFAR1ALDH1A1SMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL22668032 | 0.85 | FFAR1 (0.70) | FFAR1FFAR4 | |
| SCHEMBL437124 | 0.85 | FFAR1 (0.70) | FFAR1FFAR4 | |
| SCHEMBL437123 | 0.85 | FFAR1 (0.70) | FFAR1FFAR4 | |
| SCHEMBL22668014 | 0.85 | FFAR1 (0.46) | FFAR1ALDH1A1SMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL15239401 | 0.84 | FFAR1 (0.76) | FFAR1ALDH1A1SMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL22653334 | 0.84 | FFAR1 (0.69) | FFAR1ALDH1A1SMN1; SMN2HTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2595952-B1 | AGONISTS OF GPR40 | CONNEXIOS LIFE SCIENCES PVT LTD (IN) | 2020-11-18 | — | — | EP | disclosed |