SCHEMBL22668263

SCHEMBL22668263

CO/N=C(\COc1ccc(COc2ccc(CCC=O)c(OCC3CC3)c2)cc1)c1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 6/20 0.49
PDE4B Q07343 4/20 0.38
PPARA Q07869 3/20 0.37
TDP1 Q9NUW8 1/20 0.36
SLC6A4 P31645 1/20 0.36
DGAT1 O75907 1/20 0.36
PPARD Q03181 5/20 0.35
ACACA Q13085 1/20 0.35
YAP1 P46937 2/20 0.35
PPARG P37231 1/20 0.35
S1PR1 P21453 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL433280 0.89 FFAR1 (0.54) FFAR1PPARAPPARDYAP1
SCHEMBL433281 0.89 FFAR1 (0.54) FFAR1PPARAPPARDYAP1
SCHEMBL22668070 0.85 FFAR1 (0.51) FFAR1PPARATDP1
SCHEMBL22668554 0.82 FFAR1 (0.62) FFAR1
SCHEMBL10258787 0.78 FFAR1 (0.59) FFAR1PPARAPPARDPPARG
SCHEMBL15239313 0.78 FFAR1 (0.59) FFAR1PPARAPPARDPPARG
SCHEMBL436122 0.77 FFAR1 (0.60) FFAR1TDP1
SCHEMBL436123 0.77 FFAR1 (0.60) FFAR1TDP1
SCHEMBL22668329 0.77 FFAR1 (0.46) FFAR1PPARATDP1PPARDPPARG
SCHEMBL435343 0.76 FFAR1 (0.57) FFAR1PPARATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2595952-B1 AGONISTS OF GPR40 CONNEXIOS LIFE SCIENCES PVT LTD (IN) 2020-11-18 EP disclosed