Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 15/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 8/20 | 0.47 |
| ▸ | RXRG | P48443 | 2/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.46 |
| ▸ | RXRB | P28702 | 1/20 | 0.46 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.42 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.42 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.41 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22668354 | 0.89 | FFAR1 (0.53) | FFAR1FFAR4PTGER4PTGER3AKR1B1 | |
| SCHEMBL459360 | 0.85 | FFAR1 (0.57) | FFAR1FFAR4RXRGRXRARXRB | |
| SCHEMBL459361 | 0.85 | FFAR1 (0.57) | FFAR1FFAR4RXRGRXRARXRB | |
| SCHEMBL22668112 | 0.83 | FFAR1 (0.54) | FFAR1FFAR4PTGER4PTGER3AKR1B1 | |
| SCHEMBL22668067 | 0.81 | FFAR1 (0.72) | FFAR1FFAR4AKR1B1 | |
| SCHEMBL22668108 | 0.80 | FFAR1 (0.56) | FFAR1FFAR4PTGER4PTGER3AKR1B1 | |
| SCHEMBL22668107 | 0.78 | APP (0.55) | FFAR1FFAR4 | |
| SCHEMBL22668435 | 0.78 | FFAR1 (0.48) | FFAR1FFAR4AKR1B1 | |
| SCHEMBL22668391 | 0.77 | FFAR1 (0.46) | FFAR1FFAR4 | |
| SCHEMBL433653 | 0.76 | FFAR1 (0.51) | FFAR1FFAR4RXRGRXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2595952-B1 | AGONISTS OF GPR40 | CONNEXIOS LIFE SCIENCES PVT LTD (IN) | 2020-11-18 | — | — | EP | disclosed |