Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22668030 | 0.88 | FFAR1 (0.55) | FFAR1PTPN1MAPTAPPHDAC8 | |
| SCHEMBL22668269 | 0.87 | PTPN1 (0.43) | FFAR1PTPN1MAPTAPPHDAC8 | |
| SCHEMBL15239318 | 0.87 | FFAR1 (0.56) | FFAR1PTPN1MAPTAPPHDAC8 | |
| SCHEMBL10258506 | 0.87 | FFAR1 (0.56) | FFAR1PTPN1MAPTAPPHDAC8 | |
| SCHEMBL15239336 | 0.87 | FFAR1 (0.56) | FFAR1PTPN1MAPTAPPHDAC8 | |
| SCHEMBL15239317 | 0.87 | FFAR1 (0.56) | FFAR1PTPN1MAPTAPPHDAC8 | |
| SCHEMBL435344 | 0.86 | FFAR1 (0.57) | FFAR1PTPN1MAPTAPPHDAC8 | |
| SCHEMBL435343 | 0.86 | FFAR1 (0.57) | FFAR1PTPN1MAPTAPPHDAC8 | |
| SCHEMBL10260721 | 0.83 | FFAR1 (0.52) | FFAR1PTPN1MAPTAPPHDAC8 | |
| SCHEMBL22668270 | 0.79 | PTPN1 (0.41) | FFAR1PTPN1MAPTAPPHDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2595952-B1 | AGONISTS OF GPR40 | CONNEXIOS LIFE SCIENCES PVT LTD (IN) | 2020-11-18 | — | — | EP | disclosed |