Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | DRD3 | P35462 | 2/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.40 |
| ▸ | ACACB | O00763 | 12/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25689519 | 0.84 | ACACB (0.37) | DRD2DRD3OPRM1GRIN2BACACB | |
| SCHEMBL24008763 | 0.83 | GRIN2B (0.43) | DRD2DRD3OPRM1GRIN2BACACB | |
| SCHEMBL29447824 | 0.83 | ACACB (0.40) | DRD2DRD3GRIN2BACACB | |
| SCHEMBL22657533 | 0.83 | ACACB (0.40) | DRD2DRD3GRIN2BACACB | |
| SCHEMBL29447821 | 0.83 | ACACB (0.40) | DRD2DRD3GRIN2BACACB | |
| SCHEMBL22668978 | 0.83 | ACACB (0.40) | DRD2DRD3GRIN2BACACB | |
| SCHEMBL22657530 | 0.83 | ACACB (0.40) | DRD2DRD3GRIN2BACACB | |
| SCHEMBL22668724 | 0.81 | LCAT (0.35) | — | |
| SCHEMBL24008762 | 0.79 | GRIN2B (0.42) | DRD2DRD3GRIN2BACACBDPP4 | |
| SCHEMBL24008434 | 0.79 | GRIN2B (0.42) | DRD2DRD3GRIN2BACACBDPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020229968-A1 | NON-LYSOSOMAL GLUCOSYLCERAMIDASE INHIBITORS AND USES THEREOF | ALECTOS THERAPEUTICS INC. (CA) | 2020-11-19 | — | — | WO | disclosed |