Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCAT | P04180 | 2/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | CXCR3 | P49682 | 5/20 | 0.33 |
| ▸ | OGA | O60502 | 1/20 | 0.32 |
| ▸ | KHK | P50053 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | DNM1L | O00429 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
| ▸ | SCD | O00767 | 1/20 | 0.30 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.30 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22668993 | 0.94 | LCAT (0.38) | LCATCTSBCTSSCTSKKCNH2 | |
| SCHEMBL24008581 | 0.83 | LCAT (0.38) | LCATCTSBCTSSCTSKKCNH2 | |
| SCHEMBL22657525 | 0.82 | LCAT (0.35) | LCATCTSBCTSSCTSKKCNH2 | |
| SCHEMBL22657696 | 0.82 | LCAT (0.35) | LCATCTSBCTSSCTSKKCNH2 | |
| SCHEMBL22657695 | 0.82 | LCAT (0.35) | LCATCTSBCTSSCTSKKCNH2 | |
| SCHEMBL22657486 | 0.82 | LCAT (0.35) | LCATCTSBCTSSCTSKKCNH2 | |
| SCHEMBL22657490 | 0.82 | LCAT (0.35) | LCATCTSBCTSSCTSKKCNH2 | |
| SCHEMBL22668743 | 0.81 | DRD2 (0.40) | — | |
| SCHEMBL23996514 | 0.79 | LCAT (0.35) | LCATCTSBCTSSCTSKKCNH2 | |
| SCHEMBL24008444 | 0.78 | LCAT (0.38) | LCATCTSBCTSSCTSKKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020229968-A1 | NON-LYSOSOMAL GLUCOSYLCERAMIDASE INHIBITORS AND USES THEREOF | ALECTOS THERAPEUTICS INC. (CA) | 2020-11-19 | — | — | WO | disclosed |