Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6689726 | 0.81 | HDAC3 (0.59) | HPGDTSHRHSD17B10ALDH1A1POLB | |
| SCHEMBL15946015 | 0.80 | CA1 (0.59) | HPGDTSHRHSD17B10ALDH1A1KMT2A | |
| SCHEMBL18748244 | 0.76 | HTR2B (0.47) | HPGDTSHRHSD17B10ALDH1A1KMT2A | |
| SCHEMBL8306836 | 0.74 | HPGD (0.48) | HPGDALDH1A1KMT2ALMNARAB9A | |
| SCHEMBL15945988 | 0.74 | KDM4E (0.60) | HPGDALDH1A1KMT2A | |
| SCHEMBL19822858 | 0.74 | MAPT (0.56) | HPGDTSHRHSD17B10ALDH1A1POLB | |
| SCHEMBL22669543 | 0.73 | SMN1; SMN2 (0.52) | TSHRHSD17B10ALDH1A1POLBKMT2A | |
| SCHEMBL11678816 | 0.73 | KMT2A (0.56) | HPGDALDH1A1KMT2ALMNARAB9A | |
| SCHEMBL11678820 | 0.73 | KMT2A (0.56) | HPGDALDH1A1KMT2ALMNARAB9A | |
| SCHEMBL3124887 | 0.73 | CA1 (0.60) | TSHRHSD17B10ALDH1A1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020230136-A1 | ACSS2 INHIBITORS AND METHODS OF USE THEREOF | METABOMED LTD (IL) | 2020-11-19 | — | — | WO | disclosed |