Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.65 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 9/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.58 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MGAM | O43451 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | SI | P14410 | 2/20 | 0.46 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30203999 | 1.00 | ALOX5 (0.65) | ALOX5ALOX5APSMN1; SMN2MAPTNPSR1 | |
| SCHEMBL30203921 | 0.91 | ALOX5 (0.59) | ALOX5ALOX5APSMN1; SMN2MAPTNPSR1 | |
| SCHEMBL22671962 | 0.86 | MAPT (0.72) | ALOX5ALOX5APSMN1; SMN2MAPTNPSR1 | |
| SCHEMBL30203871 | 0.84 | MAPT (0.66) | ALOX5ALOX5APSMN1; SMN2MAPTNPSR1 | |
| SCHEMBL2947037 | 0.84 | MAPT (0.66) | ALOX5ALOX5APSMN1; SMN2MAPTNPSR1 | |
| SCHEMBL2940825 | 0.83 | SMN1; SMN2 (0.48) | ALOX5ALOX5APSMN1; SMN2MAPTNPSR1 | |
| SCHEMBL11994492 | 0.83 | ALOX5 (0.48) | ALOX5ALOX5APSMN1; SMN2MAPTNPSR1 | |
| SCHEMBL2946439 | 0.82 | ALOX5 (0.53) | ALOX5ALOX5APSMN1; SMN2MAPTNPSR1 | |
| SCHEMBL2939968 | 0.81 | SMN1; SMN2 (0.46) | ALOX5ALOX5APSMN1; SMN2MAPTNPSR1 | |
| SCHEMBL12939004 | 0.81 | ALOX5 (0.46) | ALOX5ALOX5APSMN1; SMN2MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020231979-A9 | SMALL MOLECULE INHIBITORS OF VIRAL REPLICATION | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2021-06-17 | — | — | WO | disclosed |
| WO-2020231979-A1 | SMALL MOLECULE INHIBITORS OF VIRAL REPLICATION | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2020-11-19 | — | — | WO | disclosed |