Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 9/20 | 0.61 |
| ▸ | CYP11B1 | P15538 | 9/20 | 0.61 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.61 |
| ▸ | CYP17A1 | P05093 | 4/20 | 0.61 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | AKT1 | P31749 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | STAT1 | P42224 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28284780 | 0.90 | CYP2A6 (0.56) | CYP11B2CYP11B1CYP19A1CYP17A1CYP2A6 | |
| SCHEMBL27656250 | 0.84 | CYP11B1 (0.57) | CYP11B2CYP11B1CYP19A1CYP17A1CYP2A6 | |
| SCHEMBL13727468 | 0.82 | CYP11B2 (0.71) | CYP11B2CYP11B1CYP19A1CYP17A1CYP2A6 | |
| SCHEMBL13727687 | 0.81 | CYP11B2 (0.65) | CYP11B2CYP11B1CYP19A1CYP17A1CYP2A6 | |
| SCHEMBL23543003 | 0.79 | CYP11B2 (0.71) | CYP11B2CYP11B1CYP19A1CYP17A1CYP2A6 | |
| SCHEMBL13728081 | 0.79 | CYP11B2 (0.67) | CYP11B2CYP11B1CYP19A1CYP17A1CYP2A6 | |
| SCHEMBL4361764 | 0.79 | PDE10A (0.51) | CYP11B2CYP11B1CYP2A6AKT1NPC1 | |
| SCHEMBL4361761 | 0.79 | PSMB5 (0.50) | CYP11B2CYP11B1CYP2A6AKT1NPC1 | |
| SCHEMBL13726447 | 0.79 | CYP19A1 (0.56) | CYP11B2CYP11B1CYP19A1CYP17A1CYP2A6 | |
| SCHEMBL26565897 | 0.78 | CYP11B2 (0.85) | CYP11B2CYP11B1CYP19A1CYP17A1CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020228430-A1 | IMIDAZO NITROGEN HETEROCYCLIC COMPOUND AND APPLICATION THEREOF | 广东阿格蕾雅光电材料有限公司 | 2020-11-19 | — | — | WO | disclosed |