Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 14/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 9/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL682819 | 0.87 | SLC6A2 (0.50) | SLC6A2SLC6A3SLC6A4ADRB2HTR1A | |
| SCHEMBL659743 | 0.87 | SLC6A2 (0.50) | SLC6A2SLC6A3SLC6A4ADRB2HTR1A | |
| SCHEMBL1552999 | 0.87 | SLC6A2 (0.50) | SLC6A2SLC6A3SLC6A4ADRB2HTR1A | |
| Methane SCHEMBL27798790 | 0.85 | SLC6A2 (0.49) | SLC6A2SLC6A3SLC6A4ADRB2HTR1A | |
| Hydrochloric Acid SCHEMBL4772964 | 0.85 | SLC6A2 (0.49) | SLC6A2SLC6A3SLC6A4ADRB2HTR1A | |
| SCHEMBL28529628 | 0.81 | SLC6A2 (0.41) | SLC6A2SLC6A3SLC6A4ADRB2HTR1A | |
| SCHEMBL27801504 | 0.79 | GRIK1 (0.42) | SLC6A2SLC6A3SLC6A4ADRB2HTR1A | |
| SCHEMBL27600200 | 0.79 | CA2 (0.40) | SLC6A2SLC6A3SLC6A4ADRB2HTR1A | |
| Trifluoroacetic Acid SCHEMBL352266 | 0.78 | GRIN1 (0.34) | SLC6A2SLC6A3SLC6A4ADRB2HTR1A | |
| Trifluoroacetic Acid SCHEMBL30674236 | 0.78 | GRIN1 (0.34) | SLC6A2SLC6A3SLC6A4ADRB2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110201657-A1 | AMIDE SUBSTITUTED INDAZOLE AND BENZOTRIAZOLE DERIVATIVES AS POLY(ADP-RIBOSE)POLYMERASE (PARP) INHIBITORS | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA (IT) | 2011-08-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110201657-A1 | AMIDE SUBSTITUTED INDAZOLE AND BENZOTRIAZOLE DERIVATIVES AS POLY(ADP-RIBOSE)POLYMERASE (PARP) INHIBITORS | PARP1, PARP3, PARP2 | SLC6A2 4111/4885KDM1A 1464/4885SLC6A3 3265/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.