Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | AKT1 | P31749 | 1/20 | 0.52 |
| ▸ | AKT2 | P31751 | 1/20 | 0.52 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.47 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MARK4 | Q96L34 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24479001 | 0.97 | AKT1 (0.53) | NPC1RAB9AAKT1AKT2ADRA1B | |
| SCHEMBL24479298 | 0.97 | AKT1 (0.53) | NPC1RAB9AAKT1AKT2ADRA1B | |
| SCHEMBL24479287 | 0.96 | AKT1 (0.52) | NPC1RAB9AAKT1AKT2ADRA1B | |
| SCHEMBL22673582 | 0.94 | NPC1 (0.51) | NPC1RAB9AAKT1AKT2ADRA1B | |
| SCHEMBL25789133 | 0.94 | NPC1 (0.48) | NPC1RAB9AAKT1AKT2ADRA1B | |
| SCHEMBL25789113 | 0.94 | AKT1 (0.52) | NPC1RAB9AAKT1AKT2ADRA1B | |
| SCHEMBL22673606 | 0.94 | AKT1 (0.52) | NPC1RAB9AAKT1AKT2ADRA1B | |
| SCHEMBL24478989 | 0.93 | AKT2 (0.55) | NPC1RAB9AAKT1AKT2ADRA1B | |
| SCHEMBL24479002 | 0.93 | AKT2 (0.55) | NPC1RAB9AAKT1AKT2ADRA1B | |
| SCHEMBL24479459 | 0.93 | AKT2 (0.55) | NPC1RAB9AAKT1AKT2ADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220169661-A1 | IMIDAZO NITROGEN HETEROCYCLIC COMPOUND AND APPLICATION THEREOF | GUANGDONG AGLAIA OPTOELECTRONIC MATERIALS CO., LTD (CN) | 2022-06-02 | — | — | US | disclosed |
| WO-2020228430-A1 | IMIDAZO NITROGEN HETEROCYCLIC COMPOUND AND APPLICATION THEREOF | 广东阿格蕾雅光电材料有限公司 | 2020-11-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220169661-A1 | IMIDAZO NITROGEN HETEROCYCLIC COMPOUND AND APPLICATION THEREOF | HCN4, IPO8, HCN1 | NPC1 461/4885RAB9A 1834/4885AKT1 2630/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.