Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21587658 | 0.71 | CNR2 (0.35) | — | |
| SCHEMBL19445953 | 0.70 | LRRK2 (0.37) | LRRK2 | |
| SCHEMBL18455078 | 0.68 | LRRK2 (0.45) | LRRK2 | |
| SCHEMBL9847140 | 0.66 | KDM4E (0.40) | JAK2LRRK2 | |
| SCHEMBL18794412 | 0.64 | AURKA (0.30) | — | |
| SCHEMBL19445999 | 0.64 | LRRK2 (0.40) | JAK2LRRK2 | |
| SCHEMBL19445988 | 0.62 | SYK (0.34) | JAK2LRRK2 | |
| SCHEMBL18451596 | 0.62 | CCNK (0.37) | LRRK2 | |
| SCHEMBL14220829 | 0.62 | — | — | |
| SCHEMBL24307118 | 0.62 | HTT (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020228817-A1 | ERK INHIBITOR AND USE THEREOF | 南京明德新药研发有限公司 | 2020-11-19 | — | — | WO | disclosed |