Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 20/20 | 0.57 |
| ▸ | CD274 | Q9NZQ7 | 20/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22769846 | 0.85 | PDCD1 (0.68) | PDCD1CD274 | |
| SCHEMBL22675462 | 0.85 | PDCD1 (0.61) | PDCD1CD274 | |
| SCHEMBL22675455 | 0.84 | PDCD1 (0.70) | PDCD1CD274 | |
| SCHEMBL24446141 | 0.79 | PDCD1 (0.63) | PDCD1CD274 | |
| SCHEMBL29558234 | 0.79 | PDCD1 (0.63) | PDCD1CD274 | |
| SCHEMBL30522145 | 0.78 | PDCD1 (0.67) | PDCD1CD274 | |
| SCHEMBL22769812 | 0.78 | PDCD1 (0.67) | PDCD1CD274 | |
| SCHEMBL22779780 | 0.77 | PDCD1 (0.71) | PDCD1CD274 | |
| SCHEMBL31593225 | 0.77 | PDCD1 (0.71) | PDCD1CD274 | |
| SCHEMBL22769830 | 0.77 | PDCD1 (0.78) | PDCD1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020228649-A1 | SUBSTITUTED PHENYLPROPENYLPYRIDINE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 上海海雁医药科技有限公司 | 2020-11-19 | — | — | WO | disclosed |