Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | S1PR5 | Q9H228 | 5/20 | 0.51 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.51 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.51 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.51 |
| ▸ | KDM2B | Q8NHM5 | 7/20 | 0.47 |
| ▸ | BCHE | P06276 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22675343 | 1.00 | SMN1; SMN2 (0.62) | SMN1; SMN2S1PR5S1PR4S1PR1S1PR3 | |
| SCHEMBL13102175 | 1.00 | SMN1; SMN2 (0.62) | SMN1; SMN2S1PR5S1PR4S1PR1S1PR3 | |
| SCHEMBL3842738 | 0.89 | SMN1; SMN2 (0.68) | SMN1; SMN2KDM2BBCHE | |
| SCHEMBL14554075 | 0.89 | S1PR5 (0.56) | SMN1; SMN2S1PR5S1PR4S1PR1S1PR3 | |
| SCHEMBL13766174 | 0.89 | S1PR5 (0.56) | SMN1; SMN2S1PR5S1PR4S1PR1S1PR3 | |
| SCHEMBL458560 | 0.88 | SMN1; SMN2 (0.61) | SMN1; SMN2S1PR5S1PR4S1PR1S1PR3 | |
| Hydrochloric Acid SCHEMBL5065549 | 0.86 | SMN1; SMN2 (0.64) | SMN1; SMN2S1PR5S1PR4S1PR1S1PR3 | |
| SCHEMBL13599987 | 0.85 | KDM2B (0.47) | SMN1; SMN2KDM2BBCHE | |
| SCHEMBL13739335 | 0.84 | SMN1; SMN2 (0.57) | SMN1; SMN2S1PR5S1PR4S1PR1S1PR3 | |
| SCHEMBL13740434 | 0.84 | SMN1; SMN2 (0.57) | SMN1; SMN2S1PR5S1PR4S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020228649-A1 | SUBSTITUTED PHENYLPROPENYLPYRIDINE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 上海海雁医药科技有限公司 | 2020-11-19 | — | — | WO | disclosed |