Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.42 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.42 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5065549 | 0.98 | SMN1; SMN2 (0.64) | SMN1; SMN2KCNH2DRD2S1PR5LTA4H | |
| Tert-Butylamine SCHEMBL28089928 | 0.91 | SMN1; SMN2 (0.54) | SMN1; SMN2KCNH2DRD2S1PR5LTA4H | |
| SCHEMBL22675343 | 0.88 | SMN1; SMN2 (0.62) | SMN1; SMN2S1PR5S1PR4S1PR1S1PR3 | |
| SCHEMBL13102175 | 0.88 | SMN1; SMN2 (0.62) | SMN1; SMN2S1PR5S1PR4S1PR1S1PR3 | |
| SCHEMBL22677330 | 0.88 | SMN1; SMN2 (0.62) | SMN1; SMN2S1PR5S1PR4S1PR1S1PR3 | |
| SCHEMBL6944812 | 0.88 | KCNH2 (0.55) | SMN1; SMN2KCNH2S1PR5S1PR4S1PR1 | |
| SCHEMBL19514340 | 0.87 | LTA4H (0.47) | SMN1; SMN2LTA4HL3MBTL1LMNA | |
| SCHEMBL396677 | 0.86 | KCNH2 (0.61) | SMN1; SMN2KCNH2S1PR5S1PR4S1PR1 | |
| SCHEMBL28272527 | 0.85 | SMN1; SMN2 (0.50) | SMN1; SMN2KCNH2DRD2EPHX1EPHX2 | |
| SCHEMBL9494162 | 0.85 | KCNH2 (0.64) | KCNH2S1PR5S1PR4S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2978765-A1 | METHODS FOR THE PREPARATION OF ALCAFTADINE | Crystal Pharma S.A.U (ES) | 2016-02-03 | — | — | EP | claimed |
| WO-2014154620-A1 | METHODS FOR THE PREPARATION OF ALCAFTADINE | CRYSTAL PHARMA S.A.U. (ES) | 2014-10-02 | — | — | WO | claimed |
| CN-115189882-A | Distributed identity authentication method based on block chain in group knowledge perception | 安徽师范大学 | 2022-10-14 | — | — | CN | disclosed |
| WO-2022212769-A1 | COMPOSITIONS FOR BINDING SPHINGOSINE-1-PHOSPHATE RECEPTOR 1 (S1P1), IMAGING OF S1P1, AND PROCESSES FOR PREPARATION THEREOF | WASHINGTON UNIVERSITY (US) | 2022-10-06 | — | — | WO | disclosed |
| WO-2022170974-A1 | TRICYCLIC DERIVATIVES USEFUL AS PARP7 INHIBITORS | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2022-08-18 | — | — | WO | disclosed |
| US-9763955-B2 | Methods and compositions for decreasing gastric emptying | PURDUE PHARMA L.P. (US) | 2017-09-19 | — | — | US | disclosed |
| CN-104854105-B | Compounds having muscarinic receptor antagonist and beta 2 adrenergic receptor agonist activity | 奇斯药制品公司 | 2017-05-17 | — | — | CN | disclosed |
| EP-2994470-A1 | QUINOLONE DERIVATIVES AS FIBROBLAST GROWTH FACTOR INHIBITORS | Principia Biopharma Inc. (US) | 2016-03-16 | — | — | EP | disclosed |
| EP-2978765-A1 | METHODS FOR THE PREPARATION OF ALCAFTADINE | Crystal Pharma S.A.U (ES) | 2016-02-03 | — | — | EP | disclosed |
| EP-1882684-B1 | PYRROLIDINE DERIVATIVE OR SALT THEREOF | ASTELLAS PHARMA INC (JP) | 2014-12-10 | — | — | EP | disclosed |
| WO-2014182829-A1 | QUINOLONE DERIVATIVES AS FIBROBLAST GROWTH FACTOR INHIBITORS | PRINCIPIA BIOPHARMA INC. (US) | 2014-11-13 | — | — | WO | disclosed |
| US-20070142268-A1 | Antibacterial compounds having a (pyrrole carboxamide)-(benzamide)-(imidazole carboxamide) motif | OSCIENT PHARMACEUTICALS CORPORATION (US) | 2007-06-21 | — | — | US | disclosed |
| CN-1889951-A | Substituted benzazoles and methods of their use as inhibitors of RAF kinase | CHIRON CORP (US) | 2007-01-03 | — | — | CN | disclosed |
| EP-1682126-A1 | SUBSTITUTED BENZAZOLES AND USE THEREOF AS INHIBITORS OF RAF KINASE | CHIRON CORPORATION (US) | 2006-07-26 | — | — | EP | disclosed |
| US-20050192287-A1 | Substituted benzazoles and methods of their use as inhibitors of Raf kinase | CHIRON CORPORATION (US) | 2005-09-01 | — | — | US | disclosed |
| WO-2005037273-A1 | SUBSTITUTED BENZAZOLES AND USE THEREOF AS INHIBITORS OF RAF KINASE | CHIRON CORPORATION (US) | 2005-04-28 | — | — | WO | disclosed |
| EP-0675889-A1 | ANTIALLERGIC TRIAZOLO(PYRROLO, THIENO OR FURANO)AZEPINE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1995-10-11 | — | — | EP | disclosed |
| WO-1994013681-A1 | ANTIALLERGIC TRIAZOLO(PYRROLO, THIENO OR FURANO)AZEPINE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1994-06-23 | — | — | WO | disclosed |
| EP-0588859-A1 | Imidazo[1,2-a](pyrrolo, thieno or furano)[3,2-d]azepine derivatives, compositions and methods of use | JANSSEN PHARMACEUTICA N.V. (BE) | 1994-03-30 | — | — | EP | disclosed |
| WO-1992022553-A1 | IMIDAZO[1,2-a](PYRROLO, THIENO OR FURANO)[3,2-d]AZEPINE DERIVATIVES, COMPOSITIONS AND METHODS OF USE | JANSSEN PHARMACEUTICA N.V. (BE) | 1992-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070142268-A1 | Antibacterial compounds having a (pyrrole carboxamide)-(benzamide)-(imidazole carboxamide) motif | AADAC, MRPL21, HDAC6 | SMN1; SMN2 4108/4885KCNH2 2131/4885DRD2 2919/4885 |
| US-20050192287-A1 | Substituted benzazoles and methods of their use as inhibitors of Raf kinase | BRAF, RAF1, ARAF | SMN1; SMN2 3544/4885KCNH2 3668/4885DRD2 4300/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.