Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.48 |
| ▸ | GJB2 | P29033 | 2/20 | 0.48 |
| ▸ | TACR2 | P21452 | 3/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.44 |
| ▸ | CDC25B | P30305 | 5/20 | 0.44 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.42 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GJA1 | P17302 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22677687 | 0.92 | NT5E (0.52) | NT5ETACR2PTPN1CDC25BSSTR4 | |
| SCHEMBL7079632 | 0.91 | NT5E (0.52) | NT5EGJB2TACR2PTPN1CDC25B | |
| SCHEMBL7597560 | 0.87 | GJB2 (0.52) | NT5EGJB2TACR2PTPN1CDC25B | |
| SCHEMBL22678402 | 0.86 | TACR2 (0.49) | NT5EGJB2TACR2PTPN1CDC25B | |
| SCHEMBL7948003 | 0.86 | NT5E (0.62) | NT5EGJB2TACR2PTPN1CDC25B | |
| SCHEMBL8317395 | 0.86 | NT5E (0.62) | NT5EGJB2TACR2PTPN1CDC25B | |
| SCHEMBL5198375 | 0.86 | TACR2 (0.51) | NT5EGJB2TACR2PTPN1CDC25B | |
| SCHEMBL5198380 | 0.86 | TACR2 (0.51) | NT5EGJB2TACR2PTPN1CDC25B | |
| SCHEMBL22073057 | 0.86 | NT5E (0.49) | NT5EPTPN1CDC25BSSTR4PTPN2 | |
| SCHEMBL22073764 | 0.84 | NT5E (0.48) | NT5EGJB2PTPN1CDC25BSSTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020232194-A1 | METHODS FOR GLYCOSYLATION | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2020-11-19 | — | — | WO | disclosed |