Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.81 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.59 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | GFER | P55789 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | ENPP3 | O14638 | 2/20 | 0.54 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.54 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22678442 | 1.00 | HPGD (0.81) | HPGDPTPN1GAAKCNK3KCNK9 | |
| SCHEMBL22678640 | 1.00 | HPGD (0.81) | HPGDPTPN1GAAKCNK3KCNK9 | |
| SCHEMBL19703413 | 0.90 | HPGD (1.00) | HPGDPTPN1GAAKCNK3KCNK9 | |
| SCHEMBL1300190 | 0.90 | HPGD (1.00) | HPGDPTPN1GAAKCNK3KCNK9 | |
| SCHEMBL4668488 | 0.88 | HPGD (0.96) | HPGDPTPN1GAAKCNK3KCNK9 | |
| SCHEMBL2184247 | 0.85 | HPGD (0.89) | HPGDPTPN1GAAKCNK3KCNK9 | |
| SCHEMBL25730750 | 0.84 | HPGD (0.87) | HPGDPTPN1GAAKCNK3KCNK9 | |
| SCHEMBL19501631 | 0.84 | HPGD (0.87) | HPGDPTPN1GAAKCNK3KCNK9 | |
| SCHEMBL8020692 | 0.84 | HPGD (0.87) | HPGDPTPN1GAAKCNK3KCNK9 | |
| SCHEMBL31401950 | 0.82 | HPGD (0.83) | HPGDPTPN1GAAKCNK3KCNK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020230134-A1 | ACSS2 INHIBITORS AND METHODS OF USE THEREOF | METABOMED LTD (IL) | 2020-11-19 | — | — | WO | disclosed |