Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 18/20 | 0.79 |
| ▸ | MEN1 | O00255 | 1/20 | 0.70 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.70 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.70 |
| ▸ | USP2 | O75604 | 1/20 | 0.70 |
| ▸ | SLCO2B1 | O94956 | 1/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.70 |
| ▸ | CA1 | P00915 | 1/20 | 0.70 |
| ▸ | CA2 | P00918 | 1/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.70 |
| ▸ | MMP1 | P03956 | 1/20 | 0.70 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.70 |
| ▸ | MAPT | P10636 | 1/20 | 0.70 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.70 |
| ▸ | HPGD | P15428 | 1/20 | 0.70 |
| ▸ | TSHR | P16473 | 1/20 | 0.70 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.70 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.70 |
| ▸ | CASP1 | P29466 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10835311 | 0.88 | BRD4 (0.74) | BRD4MEN1ABCC3ABCC4USP2 | |
| SCHEMBL10834280 | 0.88 | BRD4 (0.74) | BRD4MEN1ABCC3ABCC4USP2 | |
| SCHEMBL10834737 | 0.87 | BRD4 (0.72) | BRD4MEN1ABCC3ABCC4USP2 | |
| SCHEMBL10834732 | 0.87 | BRD4 (0.72) | BRD4MEN1ABCC3ABCC4USP2 | |
| SCHEMBL10242038 | 0.84 | BRD4 (1.00) | BRD4MEN1ABCC3ABCC4USP2 | |
| SCHEMBL15496568 | 0.84 | BRD4 (1.00) | BRD4MEN1ABCC3ABCC4USP2 | |
| SCHEMBL15496570 | 0.84 | BRD4 (1.00) | BRD4MEN1ABCC3ABCC4USP2 | |
| SCHEMBL30758847 | 0.83 | BRD4 (0.80) | BRD4MEN1ABCC3ABCC4USP2 | |
| Sulfasalazine SCHEMBL4515 | 0.82 | SLC7A11 (1.00) | BRD4MEN1ABCC3ABCC4USP2 | |
| Sulfasalazine SCHEMBL4514 | 0.82 | SLC7A11 (1.00) | BRD4MEN1ABCC3ABCC4USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200360356-A1 | SULFASALAZINE SALTS, PRODUCTION PROCESSES AND USES | MEDAC GESELLSCHAFT FUER KLINISCHE SPEZIALPRAEPARATE MBH (DE) | 2020-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200360356-A1 | SULFASALAZINE SALTS, PRODUCTION PROCESSES AND USES | TPMT, SI, IL5 | BRD4 2078/4885MEN1 1063/4885ABCC3 2128/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.