Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | HTR7 | P34969 | 2/20 | 0.38 |
| ▸ | HTR2B | P41595 | 2/20 | 0.38 |
| ▸ | HTR6 | P50406 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30797718 | 0.80 | SLC6A4 (0.46) | HTR1AKDM4EHSD17B10MEN1CYP3A4 | |
| SCHEMBL9790419 | 0.80 | SLC6A4 (0.46) | HTR1AKDM4EHSD17B10MEN1CYP3A4 | |
| SCHEMBL29904413 | 0.75 | HTR1A (0.46) | HTR1AKDM4EHSD17B10MEN1CYP3A4 | |
| SCHEMBL23249538 | 0.75 | HTR1A (0.46) | HTR1AKDM4EHSD17B10MEN1CYP3A4 | |
| SCHEMBL23248781 | 0.75 | HTR1A (0.46) | HTR1AKDM4EHSD17B10MEN1CYP3A4 | |
| SCHEMBL23248780 | 0.75 | HTR1A (0.46) | HTR1AKDM4EHSD17B10MEN1CYP3A4 | |
| SCHEMBL4797051 | 0.73 | DRD3 (0.59) | HTR1ADRD2DRD3HTR1D | |
| SCHEMBL23261873 | 0.72 | MEN1 (0.42) | KDM4EHSD17B10MEN1CYP3A4MAPT | |
| SCHEMBL26266600 | 0.72 | MEN1 (0.52) | KDM4EHSD17B10MEN1CYP3A4MAPT | |
| SCHEMBL3658074 | 0.68 | MEN1 (0.44) | HTR1AKDM4EHSD17B10MEN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020232255-A1 | COMPOUNDS FOR THE TREATMENT OF NEURODEGENERATIVE AND METABOLIC DISORDERS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2020-11-19 | — | — | WO | disclosed |