SCHEMBL22680481

SCHEMBL22680481

c1ccc(C2(c3ccccc3)c3ccccc3-c3c(Nc4cccc5c4Cc4ccccc4-5)cccc32)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.43
RAB9A P51151 2/20 0.43
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
KDM4E B2RXH2 2/20 0.36
LMNA P02545 2/20 0.36
MAPT P10636 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
OPRK1 P41145 1/20 0.36
PNMT P11086 1/20 0.35
HTR7 P34969 1/20 0.33
HTR2B P41595 1/20 0.33
KCNK2 O95069 1/20 0.32
KCNK10 P57789 1/20 0.32
KCNK18 Q7Z418 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
KDR P35968 1/20 0.32
ALDH1A1 P00352 1/20 0.32
HPGD P15428 1/20 0.32
PGR P06401 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21665617 0.82 MEN1 (0.49) MEN1KMT2AKDM4ELMNAMAPT
SCHEMBL23696838 0.79 MEN1 (0.46) MEN1KMT2AKDM4ELMNAMAPT
SCHEMBL70002 0.78 NPC1 (0.62) NPC1RAB9AMEN1KMT2AKDM4E
SCHEMBL22662321 0.78 FABP4 (0.43) MEN1KMT2AKDM4ELMNAMAPT
SCHEMBL29484648 0.78 MEN1 (0.43) MEN1KMT2AKDM4ELMNAMAPT
SCHEMBL16985883 0.78 MEN1 (0.43) MEN1KMT2AKDM4ELMNAMAPT
SCHEMBL15840199 0.77 KMT2A (0.40) MEN1KMT2AKDM4ELMNAMAPT
SCHEMBL23482470 0.77 MEN1 (0.40) MEN1KMT2AKDM4ELMNAMAPT
SCHEMBL23696834 0.76 MEN1 (0.42) MEN1KMT2AKDM4ELMNAMAPT
SCHEMBL25034288 0.76 CYP3A4 (0.46) NPC1RAB9AMEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11637248-B2 Organic electric element comprising compound for organic electric element and electronic device thereof DUK SAN NEOLUX CO., LTD. (KR) 2023-04-25 US disclosed
US-20200365815-A1 ORGANIC ELECTRIC ELEMENT COMPRISING COMPOUND FOR ORGANIC ELECTRIC ELEMENT AND ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2020-11-19 US disclosed