Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20002231 | 0.78 | EPHX1 (0.34) | — | |
| SCHEMBL1840371 | 0.72 | EPHX2 (0.40) | — | |
| SCHEMBL14045489 | 0.71 | — | — | |
| SCHEMBL13949109 | 0.70 | ATP1A1 (0.40) | — | |
| SCHEMBL15116706 | 0.70 | ATP1A1 (0.40) | — | |
| SCHEMBL18084128 | 0.70 | ATP1A1 (0.40) | — | |
| SCHEMBL10019507 | 0.68 | — | — | |
| SCHEMBL14372530 | 0.68 | ATP1A1 (0.34) | — | |
| SCHEMBL15116651 | 0.68 | GRM2 (0.31) | — | |
| SCHEMBL3470932 | 0.67 | FFAR3 (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3738954-A1 | METHOD OF PREPARATION OF SUBSTITUTED 2,4-DIAMINO-PYRIMIDINE-5-CARBOXAMIDES | Signal Pharmaceuticals, LLC (US) | 2020-11-18 | — | — | EP | disclosed |