SCHEMBL2268149

SCHEMBL2268149

O=C(Cl)c1cncc(C(=O)Cl)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 6/20 0.48
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44
KDM4E B2RXH2 4/20 0.43
ALDH1A1 P00352 4/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
POLB P06746 1/20 0.43
LMNA P02545 1/20 0.43
DDO Q99489 1/20 0.43
PTGS2 P35354 5/20 0.39
PTGS1 P23219 4/20 0.39
ATM Q13315 1/20 0.39
ALOX15 P16050 1/20 0.36
HTT P42858 1/20 0.36
APP P05067 1/20 0.34
GAA P10253 1/20 0.34
HCAR3 P49019 1/20 0.34
MKNK1 Q9BUB5 1/20 0.34
MKNK2 Q9HBH9 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8792391 0.91 HCAR2 (0.63) HCAR2CYP2C9CYP2C19KDM4EALDH1A1
SCHEMBL5228608 0.85 KDM4E (0.50) HCAR2CYP2C9CYP2C19KDM4EALDH1A1
SCHEMBL4196968 0.85 HCAR2 (0.69) HCAR2PTGS2PTGS1MKNK1MKNK2
SCHEMBL4196322 0.84 HCAR2 (0.67) HCAR2CYP2C9CYP2C19KDM4EALDH1A1
Hydrochloric Acid SCHEMBL3822418 0.84 HCAR2 (0.67) HCAR2PTGS2PTGS1MKNK1MKNK2
SCHEMBL31134038 0.84 HCAR2 (0.67) HCAR2CYP2C9CYP2C19KDM4EALDH1A1
SCHEMBL2584679 0.84 HCAR2 (0.67) HCAR2CYP2C9CYP2C19KDM4EALDH1A1
SCHEMBL13191629 0.84 HCAR2 (0.41) HCAR2CYP2C9CYP2C19KDM4EALDH1A1
SCHEMBL29597600 0.84 POLB (0.67) HCAR2KDM4EALDH1A1MEN1KMT2A
SCHEMBL486303 0.84 POLB (0.67) HCAR2KDM4EALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 132 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3412732-B1 POLYIMIDE-BASED BLOCK COPOLYMER FILM LG CHEMICAL LTD (KR) 2025-02-19 EP claimed
CN-114983931-A Preparation method and application of injection type pyridine amide derivative micromolecule in-situ gel preparation 赣南师范大学 2022-09-02 CN claimed
US-10717819-B2 Polyimide-based block copolymer film LG CHEM, LTD. (KR) 2020-07-21 US claimed
US-20190153159-A1 POLYIMIDE-BASED BLOCK COPOLYMER FILM LG CHEM, LTD. (KR) 2019-05-23 US claimed
CN-109071944-A Polyimide-based block copolymer films 株式会社LG化学 2018-12-21 CN claimed
EP-3412732-A1 POLYIMIDE-BASED BLOCK COPOLYMER FILM LG Chem, Ltd. (KR) 2018-12-12 EP claimed
WO-2018093118-A1 POLYIMIDE-BASED BLOCK COPOLYMER FILM 주식회사 엘지화학 2018-05-24 WO claimed
EP-0561782-B1 PROCESS FOR PREPARATION OF AROMATIC THIOL ESTERS ROHM & HAAS (US) 1996-04-17 EP claimed
US-20250376543-A1 HYALURONIC ACID-COLLAGEN COPOLYMER COMPOSITIONS AND MEDICAL APPLICATIONS THEREOF SHANGHAI QISHENG BIOLOGICAL PREPARATION CO LTD (CN) 2025-12-11 US disclosed
US-12304974-B2 Hyaluronic acid-collagen copolymer compositions and medical applications thereof SHANGHAI QISHENG BIOLOGICAL PREPARATION CO., LTD. (CN) 2025-05-20 US disclosed
EP-4518842-A1 NOVEL LIPID-BASED SMALL MOLECULE INTEGRIN RECEPTOR-LIGAND AGONIST ADJUVANTS CARRIER COMPOSITIONS, INTEGRIN AGONIST ADJUVANT PHARMACEUTICAL COMPOSITIONS THEREFROM, AND METHODS FOR MAKING AND USING SAME 7 Hills Pharma Inc. (US) 2025-03-12 EP disclosed
CN-119546288-A Novel lipid-based small molecule integrin receptor-ligand agonist adjuvant carrier compositions, integrin agonist adjuvant pharmaceutical compositions thereof, and methods of making and using the same 7山药物公司 2025-02-28 CN disclosed
EP-3412732-B1 POLYIMIDE-BASED BLOCK COPOLYMER FILM LG CHEMICAL LTD (KR) 2025-02-19 EP disclosed
EP-3486271-B1 POLYIMIDE-BASED BLOCK COPOLYMER AND POLYIMIDE-BASED FILM COMPRISING SAME LG CHEMICAL LTD (KR) 2025-02-19 EP disclosed
US-4614770-A HYDROCYANATION OF CARBONYL, THIOCARBONYL OR IMINO GROUPS; POLYMERS BEARING PYRIDINE-NUCLEUS RING SUBSTITUTED BY CARBOXAMIDE GROUPS ALLIED CORPORATION (US) 1986-09-30 US disclosed
EP-0180897-A2 5-Fluorouracil derivatives OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1986-05-14 EP disclosed
US-4214071-A Amide-imide polymers WESTINGHOUSE ELECTRIC CORP. (US) 1980-07-22 US disclosed
US-4118232-A Photographic material containing sulphonic acid group containing disazo dyestuffs CIBA-GEIGY AG (CH) 1978-10-03 US disclosed
US-4051123-A Sulfonic-acid-group containing disazo dyestuffs CIBA-GEIGY AG (CH) 1977-09-27 US disclosed
US-3931142-A Heterocyclic containing disazo compounds CIBA-GEIGY AG (CH) 1976-01-06 US disclosed