Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 2/20 | 0.43 |
| ▸ | ACR | P10323 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | THRA | P10827 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2270314 | 0.95 | PRSS1 (0.47) | PRSS1ACRTHRBNPC1LMNA | |
| SCHEMBL19755943 | 0.88 | POLB (0.45) | PRSS1ACRNPC1LMNACYP1A2 | |
| SCHEMBL3344394 | 0.85 | PRSS1 (0.49) | PRSS1ACRTHRBNPC1LMNA | |
| SCHEMBL15855553 | 0.84 | THRB (0.60) | PRSS1ACRTHRBNPC1LMNA | |
| SCHEMBL16379487 | 0.84 | THRB (0.60) | PRSS1ACRTHRBNPC1LMNA | |
| SCHEMBL3346948 | 0.84 | PRSS1 (0.59) | PRSS1ACRTHRBNPC1LMNA | |
| SCHEMBL16379471 | 0.83 | THRB (0.58) | PRSS1ACRTHRBNPC1LMNA | |
| SCHEMBL16379475 | 0.83 | THRB (0.58) | PRSS1ACRTHRBNPC1LMNA | |
| SCHEMBL21924985 | 0.83 | THRB (0.54) | THRBLMNACYP3A4KMT2ASMN1; SMN2 | |
| SCHEMBL21924984 | 0.83 | THRB (0.54) | THRBLMNACYP3A4KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110206751-A1 | STIMULATABLE ASYMMETRICAL POLYMERSOME | INSTITUT CURIE (FR) | 2011-08-25 | — | — | US | claimed |
| US-20110206751-A1 | STIMULATABLE ASYMMETRICAL POLYMERSOME | INSTITUT CURIE (FR) | 2011-08-25 | — | — | US | disclosed |