Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 1/20 | 0.53 |
| ▸ | WNT3A | P56704 | 1/20 | 0.53 |
| ▸ | PTPRC | P08575 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | CTSG | P08311 | 2/20 | 0.43 |
| ▸ | KLK7 | P49862 | 2/20 | 0.43 |
| ▸ | KLK14 | Q9P0G3 | 2/20 | 0.43 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | DHFR | P00374 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22681887 | 0.85 | BACE1 (0.51) | CTNNB1WNT3AKDM4CKCNH2LMNA | |
| SCHEMBL17378737 | 0.85 | CTNNB1 (0.45) | CTNNB1WNT3AKDM4CKCNH2ESR1 | |
| SCHEMBL22681889 | 0.81 | CD274 (0.42) | CTNNB1WNT3AKDM4CPDK2ADORA1 | |
| SCHEMBL6951619 | 0.79 | ADORA1 (0.52) | PTPRCPTPN1PDGFRBFGFR1KDR | |
| SCHEMBL22681721 | 0.78 | MEN1 (0.44) | CTNNB1WNT3AKDM4CKCNH2MEN1 | |
| SCHEMBL22681646 | 0.78 | AXL (0.47) | CTSGKLK7KLK14KLK5KDM4C | |
| SCHEMBL28137011 | 0.76 | KCNH2 (0.52) | CTNNB1WNT3AKCNH2 | |
| SCHEMBL22681657 | 0.75 | CTNNB1 (0.45) | CTNNB1WNT3AKDM4CKCNH2ALDH1A1 | |
| SCHEMBL22681716 | 0.75 | ESR2 (0.43) | KDM4CKCNH2HSD17B3MEN1ALDH1A1 | |
| SCHEMBL22681979 | 0.75 | KCNH2 (0.44) | CTNNB1WNT3AKDM4CKCNH2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3160952-B1 | HISTONE DEMETHYLASE INHIBITORS | CELGENE QUANTICEL RES INC (US) | 2020-12-02 | — | — | EP | disclosed |
| EP-3741749-A1 | HISTONE DEMETHYLASE INHIBITORS | Celgene Quanticel Research, Inc. (US) | 2020-11-25 | — | — | EP | disclosed |
| EP-3738960-A1 | HISTONE DEMETHYLASE INHIBITORS | Celgene Quanticel Research, Inc. (US) | 2020-11-18 | — | — | EP | disclosed |