SCHEMBL2268255

SCHEMBL2268255

CCN(CC)Cc1ccccc1[SiH3]

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.48
MAPT P10636 3/20 0.46
HSD17B10 Q99714 2/20 0.46
KDM4E B2RXH2 2/20 0.46
MEN1 O00255 2/20 0.46
ALDH1A1 P00352 2/20 0.46
KMT2A Q03164 2/20 0.46
HPGD P15428 1/20 0.46
CYP1A2 P05177 1/20 0.44
CYP2D6 P10635 1/20 0.44
NFKB1 P19838 1/20 0.44
CYP2C19 P33261 1/20 0.44
POLB P06746 1/20 0.43
THRB P10828 1/20 0.43
APEX1 P27695 1/20 0.43
MAPK1 P28482 1/20 0.43
HTT P42858 1/20 0.43
RECQL P46063 1/20 0.43
CACNA1B Q00975 1/20 0.43
APBA1 Q02410 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7768256 0.84 TSHR (0.57) TSHRMAPTHSD17B10KDM4EMEN1
SCHEMBL31153347 0.84 TSHR (0.57) TSHRMAPTHSD17B10KDM4EMEN1
SCHEMBL2267945 0.77 SLC6A4 (0.47) TSHRHSD17B10KDM4EMEN1ALDH1A1
SCHEMBL13469121 0.77 TSHR (0.52) TSHRMAPTHSD17B10KDM4EMEN1
SCHEMBL10652519 0.77 CNR2 (0.44) TSHRKDM4EALDH1A1MAPK1BCHE
SCHEMBL88662 0.76
SCHEMBL12677859 0.76 MAPT (0.70) TSHRMAPTHSD17B10KDM4EMEN1
SCHEMBL26686946 0.76 TSHR (0.50) TSHRMAPTHSD17B10KDM4EMEN1
SCHEMBL2101250 0.75 CHRM2 (0.39) TSHRMAPTHSD17B10KDM4EMEN1
SCHEMBL4049148 0.74 TSHR (0.81) TSHRMAPTHSD17B10KDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8404584-B2 Method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2013-03-26 US disclosed
US-20110207319-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2011-08-25 US disclosed