SCHEMBL2267945

SCHEMBL2267945

CN(C)Cc1ccccc1[SiH3]

nearest known ligand 0.52

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 13/20 0.47
SLC6A2 P23975 10/20 0.47
ALDH1A1 P00352 3/20 0.46
TSHR P16473 2/20 0.46
SLC6A3 Q01959 9/20 0.44
LMNA P02545 1/20 0.44
HTR2A P28223 2/20 0.43
CYP2D6 P10635 3/20 0.42
KDM4E B2RXH2 2/20 0.42
CYP3A4 P08684 2/20 0.42
MEN1 O00255 1/20 0.42
CYP2C19 P33261 1/20 0.42
KMT2A Q03164 1/20 0.42
HSD17B10 Q99714 1/20 0.42
CYP1A2 P05177 2/20 0.42
HPGD P15428 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29729780 0.82 ALDH1A1 (0.57) SLC6A4SLC6A2ALDH1A1TSHRSLC6A3
SCHEMBL125255 0.82 ALDH1A1 (0.57) SLC6A4SLC6A2ALDH1A1TSHRSLC6A3
SCHEMBL2268255 0.77 TSHR (0.48) ALDH1A1TSHRLMNACYP2D6KDM4E
SCHEMBL88662 0.74
SCHEMBL12188870 0.73 SLC6A4 (0.48) SLC6A4SLC6A2ALDH1A1TSHRSLC6A3
Alcohol SCHEMBL28875867 0.73 SLC6A4 (0.53) SLC6A4SLC6A2ALDH1A1TSHRSLC6A3
SCHEMBL20657966 0.73 SLC6A4 (0.48) SLC6A4SLC6A2ALDH1A1TSHRSLC6A3
SCHEMBL329228 0.73 SLC6A4 (0.48) SLC6A4SLC6A2ALDH1A1TSHRSLC6A3
SCHEMBL9621569 0.73 TAAR1 (0.39) TSHRCYP3A4CYP2C19CYP1A2
Fluoride SCHEMBL27930947 0.72 GABRA1 (0.46) ALDH1A1TSHRCYP2D6HSD17B10HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8404584-B2 Method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2013-03-26 US disclosed
US-20110207319-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2011-08-25 US disclosed
EP-0861845-B1 Silicon-containing compound and organic electroluminescence device using the same SUMITOMO CHEMICAL CO (JP) 2003-05-28 EP disclosed