SCHEMBL2268392

SCHEMBL2268392

CCNc1ccc([SiH3])c(C(C)CC)c1NCC

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.32
TSHR P16473 1/20 0.32
RECQL P46063 1/20 0.32
IDO1 P14902 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2104723 0.86 CYP3A4 (0.33) CYP3A4TSHRRECQLIDO1
SCHEMBL2274658 0.86 IDO1 (0.33) CYP3A4TSHRRECQLIDO1
SCHEMBL2269720 0.82
SCHEMBL2268973 0.79
SCHEMBL233709 0.76 CYP3A4 (0.38) CYP3A4TSHRRECQLIDO1
SCHEMBL2269107 0.75 IDO1 (0.34) CYP3A4TSHRRECQLIDO1
SCHEMBL2270655 0.75 CYP2C9 (0.31) TSHR
SCHEMBL2099502 0.72 CYP3A4 (0.35) CYP3A4TSHRRECQLIDO1
SCHEMBL2273897 0.70
SCHEMBL2269740 0.69 CYP3A4 (0.33) CYP3A4TSHRRECQLIDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8404584-B2 Method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2013-03-26 US disclosed
US-20110207319-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2011-08-25 US disclosed