SCHEMBL2104723

SCHEMBL2104723

CCNc1ccc([SiH3])c(C(C)C)c1NCC

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.33
TSHR P16473 1/20 0.33
RECQL P46063 1/20 0.33
IDO1 P14902 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2268392 0.86 CYP3A4 (0.32) CYP3A4TSHRRECQLIDO1
SCHEMBL2269107 0.85 IDO1 (0.34) CYP3A4TSHRRECQLIDO1
SCHEMBL2102372 0.81 MITF (0.30)
SCHEMBL233709 0.79 CYP3A4 (0.38) CYP3A4TSHRRECQLIDO1
SCHEMBL2268858 0.76 MEN1 (0.36) CYP3A4TSHRRECQLIDO1
SCHEMBL2274658 0.75 IDO1 (0.33) CYP3A4TSHRRECQLIDO1
SCHEMBL2099502 0.74 CYP3A4 (0.35) CYP3A4TSHRRECQLIDO1
SCHEMBL2099891 0.73
SCHEMBL2269740 0.71 CYP3A4 (0.33) CYP3A4TSHRRECQLIDO1
SCHEMBL2102937 0.69 MEN1 (0.39) CYP3A4TSHRRECQLIDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8404584-B2 Method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2013-03-26 US disclosed
US-8164166-B2 Interfacial roughness reducing film, wiring layer, semiconductor device, and method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2012-04-24 US disclosed
US-20110207319-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2011-08-25 US disclosed
US-20090085170-A1 INTERFACIAL ROUGHNESS REDUCING FILM, WIRING LAYER, SEMICONDUCTOR DEVICE, AND METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2009-04-02 US disclosed