Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPFFR1 | Q9GZQ6 | 5/20 | 0.48 |
| ▸ | NPFFR2 | Q9Y5X5 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | SCN4A | P35499 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5768492 | 1.00 | NPFFR1 (0.48) | NPFFR1NPFFR2KMT2AL3MBTL1DRD4 | |
| SCHEMBL4675629 | 0.96 | KMT2A (0.47) | NPFFR1NPFFR2KMT2AL3MBTL1DRD4 | |
| SCHEMBL5232335 | 0.90 | KMT2A (0.44) | NPFFR1NPFFR2KMT2AL3MBTL1DRD4 | |
| SCHEMBL5235530 | 0.90 | KMT2A (0.44) | NPFFR1NPFFR2KMT2AL3MBTL1DRD4 | |
| SCHEMBL7518231 | 0.87 | NPFFR1 (0.48) | NPFFR1NPFFR2KMT2AL3MBTL1BCHE | |
| SCHEMBL14087066 | 0.87 | NPFFR1 (0.50) | NPFFR1NPFFR2KMT2AL3MBTL1BCHE | |
| SCHEMBL34473649 | 0.85 | KMT2A (0.47) | NPFFR1NPFFR2KMT2AL3MBTL1BCHE | |
| SCHEMBL16032495 | 0.84 | KMT2A (0.47) | NPFFR1NPFFR2KMT2AL3MBTL1BCHE | |
| SCHEMBL16032497 | 0.84 | KMT2A (0.47) | NPFFR1NPFFR2KMT2AL3MBTL1BCHE | |
| SCHEMBL16032494 | 0.84 | KMT2A (0.47) | NPFFR1NPFFR2KMT2AL3MBTL1BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1693364-B1 | INTERMEDIATES FOR THE PRODUCTION OF OPTICALLY ACTIVE CYCLOPROPYLAMINE DERIVATIVES AND PROCESS FOR THE PRODUCTION OF THE INTERMEDIATES | DAIICHI SANKYO CO LTD (JP) | 2015-05-20 | — | — | EP | disclosed |
| US-7994344-B2 | Intermediates for the production of optically active cyclopropylamine derivatives and process for the production of the intermediates | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2011-08-09 | — | — | US | disclosed |
| US-20090240066-A1 | INTERMEDIATES FOR THE PRODUCTION OF OPTICALLY ACTIVE CYCLOPROPYLAMINE DERIVATIVES AND PROCESS FOR THE PRODUCTION OF THE INTERMEDIATES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2009-09-24 | — | — | US | disclosed |
| US-7569599-B2 | Intermediates for the production of optically active cyclopropylamine derivatives and process for the production of the intermediates | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2009-08-04 | — | — | US | disclosed |
| US-20070117988-A1 | Intermediates for the production of optically active cyclopropylamine derivatives and process for the production of the intermediates | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2007-05-24 | — | — | US | disclosed |
| EP-1693364-A1 | INTERMEDIATES FOR THE PRODUCTION OF OPTICALLY ACTIVE CYCLOPROPYLAMINE DERIVATIVES AND PROCESS FOR THE PRODUCTION OF THE INTERMEDIATES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-08-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070117988-A1 | Intermediates for the production of optically active cyclopropylamine derivatives and process for the production of the intermediates | RAP1A, RHOA, MGMT | NPFFR1 938/4885NPFFR2 1356/4885KMT2A 1498/4885 |
| US-20090240066-A1 | INTERMEDIATES FOR THE PRODUCTION OF OPTICALLY ACTIVE CYCLOPROPYLAMINE DERIVATIVES AND PROCESS FOR THE PRODUCTION OF THE INTERMEDIATES | RAP1A, RHOA, MGMT | NPFFR1 938/4885NPFFR2 1356/4885KMT2A 1498/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.