Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.46 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 4/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | SCN4A | P35499 | 2/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | MME | P08473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5768492 | 0.96 | NPFFR1 (0.48) | KMT2AL3MBTL1NPFFR1NPFFR2MEN1 | |
| SCHEMBL2268507 | 0.96 | NPFFR1 (0.48) | KMT2AL3MBTL1NPFFR1NPFFR2MEN1 | |
| SCHEMBL5232335 | 0.88 | KMT2A (0.44) | KMT2AL3MBTL1NPFFR1NPFFR2MEN1 | |
| SCHEMBL5235530 | 0.88 | KMT2A (0.44) | KMT2AL3MBTL1NPFFR1NPFFR2MEN1 | |
| SCHEMBL34473649 | 0.88 | KMT2A (0.47) | KMT2AL3MBTL1NPFFR1NPFFR2MEN1 | |
| SCHEMBL16032495 | 0.87 | KMT2A (0.47) | KMT2AL3MBTL1NPFFR1NPFFR2MEN1 | |
| SCHEMBL16032494 | 0.87 | KMT2A (0.47) | KMT2AL3MBTL1NPFFR1NPFFR2MEN1 | |
| SCHEMBL16032497 | 0.87 | KMT2A (0.47) | KMT2AL3MBTL1NPFFR1NPFFR2MEN1 | |
| SCHEMBL7518231 | 0.85 | NPFFR1 (0.48) | KMT2AL3MBTL1NPFFR1NPFFR2MEN1 | |
| SCHEMBL14087066 | 0.85 | NPFFR1 (0.50) | KMT2AL3MBTL1NPFFR1NPFFR2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1304329-B1 | Pyridonecarboxylic acid derivatives and their use as antibacterial agents | DAIICHI SANKYO CO LTD (JP) | 2008-10-15 | — | — | EP | disclosed |
| EP-1304329-A2 | Pyridonecarboxylic acid derivatives and their use as antibacterial agents | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2003-04-23 | — | — | EP | disclosed |
| US-5849757-A | Pyridonecarboxylic acid derivatives substituted by a bicyclic amino group as antibacterials | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1998-12-15 | — | — | US | disclosed |
| EP-0807630-A1 | HETEROCYCLIC COMPOUNDS | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1997-11-19 | — | — | EP | disclosed |