⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16075603 | 0.78 | — | — | |
| SCHEMBL13381001 | 0.70 | — | — | |
| SCHEMBL16078916 | 0.70 | — | — | |
| SCHEMBL19979162 | 0.70 | NOS3 (0.31) | — | |
| SCHEMBL15791000 | 0.70 | NOS3 (0.31) | — | |
| SCHEMBL1929832 | 0.69 | — | — | |
| SCHEMBL1929833 | 0.69 | — | — | |
| SCHEMBL10000238 | 0.69 | — | — | |
| SCHEMBL18412341 | 0.69 | — | — | |
| SCHEMBL13762106 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116924929-A | Synthesis method of iobixin isomer | 重庆圣华曦药业股份有限公司 | 2023-10-24 | — | — | CN | claimed |
| CN-116924929-A | Synthesis method of iobixin isomer | 重庆圣华曦药业股份有限公司 | 2023-10-24 | — | — | CN | disclosed |
| US-11364248-B2 | Compounds that inhibit Mcl-1 protein | AMGEN INC. (US) | 2022-06-21 | — | — | US | disclosed |
| US-20200360399-A1 | COMPOUNDS THAT INHIBIT MCL-1 PROTEIN | AMGEN INC. (US) | 2020-11-19 | — | — | US | disclosed |