Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 3/20 | 0.38 |
| ▸ | WDR91 | A4D1P6 | 3/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
| ▸ | PDE2A | O00408 | 3/20 | 0.33 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 3/20 | 0.32 |
| ▸ | DRD4 | P21917 | 3/20 | 0.32 |
| ▸ | DRD3 | P35462 | 3/20 | 0.32 |
| ▸ | TACR3 | P29371 | 1/20 | 0.32 |
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22684825 | 0.88 | WDR91 (0.48) | AKT1WDR91BTKCXCR3HDAC6 | |
| SCHEMBL22685332 | 0.87 | AKT1 (0.38) | AKT1WDR91CTSLCTSBCTSS | |
| SCHEMBL22684827 | 0.86 | AKT1 (0.39) | AKT1WDR91CTSLCTSBCTSS | |
| SCHEMBL22686781 | 0.84 | BTK (0.38) | AKT1CTSLCTSBCTSSBTK | |
| SCHEMBL22685160 | 0.81 | WDR91 (0.41) | AKT1WDR91CTSLCTSBCTSS | |
| SCHEMBL22685161 | 0.77 | PTPN1 (0.46) | CTSLCTSBCTSSBTKHDAC6 | |
| SCHEMBL22657417 | 0.77 | MKNK1 (0.45) | AKT1CTSLCTSBCTSSBTK | |
| SCHEMBL22684823 | 0.76 | SCN9A (0.39) | AKT1CTSLCTSBCTSSBTK | |
| SCHEMBL22686795 | 0.76 | BTK (0.38) | AKT1CTSLCTSBCTSSBTK | |
| SCHEMBL22657410 | 0.74 | WDR91 (0.40) | AKT1WDR91CTSLCTSBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020228823-A1 | NOVEL AMIDE COMPOUNDS AND USES THEREOF | HUTCHISON MEDIPHARMA LIMITED (CN) | 2020-11-19 | — | — | WO | disclosed |