Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.46 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.46 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.40 |
| ▸ | BTK | Q06187 | 1/20 | 0.38 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.36 |
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22685172 | 0.96 | PTPN1 (0.44) | PTPN1PTPN6PTPN11CNR2NPC1 | |
| SCHEMBL22684819 | 0.88 | PTPN1 (0.42) | PTPN1PTPN6PTPN11CNR2NPC1 | |
| SCHEMBL22685160 | 0.87 | WDR91 (0.41) | PTPN1PTPN6PTPN11CNR2HDAC2 | |
| SCHEMBL22685168 | 0.86 | PTPN1 (0.40) | PTPN1PTPN6PTPN11CNR2NPC1 | |
| SCHEMBL22657405 | 0.79 | WDR91 (0.39) | PTPN1PTPN6PTPN11HDAC2HDAC3 | |
| SCHEMBL28547259 | 0.79 | NPC1 (0.44) | PTPN1PTPN6PTPN11CNR2NPC1 | |
| SCHEMBL22685186 | 0.79 | PTPN1 (0.48) | PTPN1PTPN6PTPN11NPC1RXFP1 | |
| SCHEMBL22657417 | 0.78 | MKNK1 (0.45) | HDAC1HDAC6BTKCTSLCTSB | |
| SCHEMBL22657410 | 0.78 | WDR91 (0.40) | NPC1HDAC2HDAC3HDAC1HDAC6 | |
| SCHEMBL22685331 | 0.77 | AKT1 (0.38) | HDAC6BTKCTSLCTSBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020228823-A1 | NOVEL AMIDE COMPOUNDS AND USES THEREOF | HUTCHISON MEDIPHARMA LIMITED (CN) | 2020-11-19 | — | — | WO | disclosed |