⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22686153 | 0.68 | — | — | |
| SCHEMBL7858362 | 0.64 | — | — | |
| SCHEMBL5751412 | 0.63 | — | — | |
| SCHEMBL15517088 | 0.60 | — | — | |
| SCHEMBL3766342 | 0.60 | CA1 (0.39) | — | |
| SCHEMBL1075701 | 0.59 | — | — | |
| SCHEMBL1527431 | 0.59 | — | — | |
| SCHEMBL7610695 | 0.59 | — | — | |
| SCHEMBL5754088 | 0.59 | — | — | |
| SCHEMBL27817868 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200369667-A1 | HETEROCYCLIC COMPOUNDS AS PRMT5 INHIBITORS | ANGEX PHARMACEUTICAL, INC. | 2020-11-26 | — | — | US | disclosed |