SCHEMBL2268626

SCHEMBL2268626

CCC[SiH](Cl)CCCCNCC

nearest known ligand 0.48

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 2/20 0.48
TSHR P16473 2/20 0.48
CYP1A2 P05177 1/20 0.48
MEN1 O00255 1/20 0.44
GLA P06280 1/20 0.44
KMT2A Q03164 1/20 0.44
KDM1A O60341 5/20 0.40
ALDH1A1 P00352 1/20 0.39
SAT1 P21673 2/20 0.34
HRH4 Q9H3N8 1/20 0.30
HRH3 Q9Y5N1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2277122 0.84 CYP2C19 (0.50) CYP2C19TSHRCYP1A2MEN1GLA
SCHEMBL2101282 0.84 TSHR (0.42) CYP2C19TSHRCYP1A2MEN1GLA
SCHEMBL2272051 0.80 EPHX1 (0.48)
SCHEMBL2271568 0.79 CYP2C19 (0.55) CYP2C19TSHRCYP1A2MEN1GLA
SCHEMBL2275399 0.77 CYP2C19 (0.52) CYP2C19TSHRCYP1A2MEN1GLA
SCHEMBL15934461 0.74 TSHR (0.44) TSHRMEN1KMT2AALDH1A1
SCHEMBL2271817 0.73
SCHEMBL2271118 0.72 CYP2C19 (0.46) CYP2C19TSHRCYP1A2MEN1GLA
SCHEMBL2274237 0.72 CYP2C19 (0.46) CYP2C19TSHRCYP1A2MEN1GLA
SCHEMBL863701 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8404584-B2 Method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2013-03-26 US disclosed
US-20110207319-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2011-08-25 US disclosed