⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16111864 | 1.00 | ALDH1A1 (0.55) | — | |
| SCHEMBL19284195 | 1.00 | — | — | |
| SCHEMBL180137 | 1.00 | — | — | |
| SCHEMBL7139174 | 0.97 | ALDH1A1 (0.52) | — | |
| SCHEMBL23045217 | 0.77 | — | — | |
| SCHEMBL2888895 | 0.77 | SLC22A6 (0.41) | — | |
| SCHEMBL9855052 | 0.77 | — | — | |
| SCHEMBL9854874 | 0.77 | — | — | |
| SCHEMBL30315700 | 0.77 | — | — | |
| SCHEMBL7271862 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117143053-A | Preparation method of (R) - (-) -3-hydroxytetrahydrofuran | 中国海洋大学 | 2023-12-01 | — | — | CN | claimed |
| US-20230399314-A1 | CD73 INHIBITOR AND USE THEREOF | Wuhan Humanwell Innovative Drug Research and Development Center Limited Company (CN) | 2023-12-14 | — | — | US | disclosed |
| US-20230399314-A1 | CD73 INHIBITOR AND USE THEREOF | Wuhan Humanwell Innovative Drug Research and Development Center Limited Company (CN) | 2023-12-14 | — | — | US | disclosed |
| US-20230399314-A1 | CD73 INHIBITOR AND USE THEREOF | Wuhan Humanwell Innovative Drug Research and Development Center Limited Company (CN) | 2023-12-14 | — | — | US | disclosed |
| CN-117143053-A | Preparation method of (R) - (-) -3-hydroxytetrahydrofuran | 中国海洋大学 | 2023-12-01 | — | — | CN | disclosed |
| EP-4242204-A1 | CD73 INHIBITOR AND USE THEREOF | Wuhan Humanwell Innovative Drug Research and Development Center Limited Company (CN) | 2023-09-13 | — | — | EP | disclosed |
| EP-4242204-A1 | CD73 INHIBITOR AND USE THEREOF | Wuhan Humanwell Innovative Drug Research and Development Center Limited Company (CN) | 2023-09-13 | — | — | EP | disclosed |
| US-11464853-B2 | Amino acid and peptide conjugates and conjugation process | AUCKLAND UNISERVICES LIMITED (NZ) | 2022-10-11 | — | — | US | disclosed |
| WO-2022095975-A1 | CD73 INHIBITOR AND USE THEREOF | 武汉人福创新药物研发中心有限公司 | 2022-05-12 | — | — | WO | disclosed |
| WO-2022095975-A1 | CD73 INHIBITOR AND USE THEREOF | 武汉人福创新药物研发中心有限公司 | 2022-05-12 | — | — | WO | disclosed |
| US-6689741-B2 | DRUGS, MEDICAL DIAGNOSIS | BARRITAULT DENIS (FR) | 2004-02-10 | — | — | US | disclosed |
| US-6677476-B1 | REDUCING HALO- OR SULFONYLOXY-SUCCINIC ACID OR DERIVATIVE WITH SUITABLE REDUCING AGENT, TREATING WITH BASE AND THEN WITH TRIMETHYLAMINE | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2004-01-13 | — | — | US | disclosed |
| CN-1352630-A | Process for preparing R-(-)-carnitine S-(-)-chlorosuccinic acid or from a derivative thereof | SIGMA TAU IND FARMACEUTI (IT) | 2002-06-05 | — | — | CN | disclosed |
| EP-1187805-A1 | PROCESS FOR PREPARING R-(-)-CARNITINE FROM S-(-)-CHLOROSUCCINIC ACID OR FROM A DERIVATIVE THEREOF | Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. (IT) | 2002-03-20 | — | — | EP | disclosed |
| US-20010021758-A1 | Drugs, medical diagnosis | BARRITAULT DENIS (FR) | 2001-09-13 | — | — | US | disclosed |
| WO-2000069808-A1 | PROCESS FOR PREPARING R-(-)-CARNITINE FROM S-(-)-CHLOROSUCCINIC ACID OR FROM A DERIVATIVE THEREOF | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2000-11-23 | — | — | WO | disclosed |
| US-5319103-A | Intermediate diastereomeric 5R,6S-6-(1R-hydroxyethyl)-2-(cis-1-oxo-3-thiolanylthio)-2-penem-carboxylic acids | PFIZER INC. (US) | 1994-06-07 | — | — | US | disclosed |
| US-5191077-A | Diastereomeric 5R,6S-6-(1R-hydroxyethyl)-2-(cis-1-oxo-3-thiolanylthio)-2-penem-3-carboxylic acids | PFIZER INC. (US) | 1993-03-02 | — | — | US | disclosed |
| US-5013729-A | Diastereomeric 5R,6S-6-(1R-hydroxyethyl)-2-(cis-1-oxo-3-thiolanylthio)-2-penem-3-carboxylic acids | PFIZER INC. (US) | 1991-05-07 | — | — | US | disclosed |
| WO-1988008845-A1 | DIASTEREOMERIC 5R,6S-6-(1R-HYDROXYETHYL)-2-(CIS-1-OXO-3-THIOLANYLTHIO)-2-PENEM-3-CARBOXYLIC ACIDS | PFIZER INC. (US) | 1988-11-17 | — | — | WO | disclosed |