Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.36 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.35 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.34 |
| ▸ | HTR1A | P08908 | 3/20 | 0.33 |
| ▸ | HTR2A | P28223 | 3/20 | 0.33 |
| ▸ | HTR2C | P28335 | 3/20 | 0.33 |
| ▸ | HTR7 | P34969 | 3/20 | 0.33 |
| ▸ | DRD3 | P35462 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30442871 | 1.00 | KDM4E (0.40) | KDM4EHPGDESR1ESR2HSD17B1 | |
| SCHEMBL22686630 | 0.93 | KDM4E (0.39) | KDM4EHPGDESR1ESR2HSD17B1 | |
| SCHEMBL22687672 | 0.89 | KDM4E (0.44) | KDM4EHPGDESR1ESR2HSD17B1 | |
| SCHEMBL22687027 | 0.89 | KDM4E (0.44) | KDM4EHPGDESR1ESR2HSD17B1 | |
| SCHEMBL30443096 | 0.89 | KDM4E (0.44) | KDM4EHPGDESR1ESR2HSD17B1 | |
| SCHEMBL22007456 | 0.89 | KDM4E (0.52) | KDM4EHPGDALOX5HTTALDH1A1 | |
| SCHEMBL22181970 | 0.89 | KDM4E (0.52) | KDM4EHPGDALOX5HTTALDH1A1 | |
| SCHEMBL22653496 | 0.88 | KDM4E (0.50) | KDM4EHPGDHTTOPRD1ALDH1A1 | |
| SCHEMBL30442802 | 0.88 | KDM4E (0.50) | KDM4EHPGDHTTOPRD1ALDH1A1 | |
| SCHEMBL22007462 | 0.86 | KDM4E (0.44) | KDM4EHPGDESR1ESR2ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200365809-A1 | ORGANIC EL DEVICE, AMINE COMPOUND HAVING BENZAZOLE RING STRUCTURE, AND METHOD IN WHICH SAID AMINE COMPOUND IS USED IN CAPPING LAYER OF ORGANIC EL DEVICE | HODOGAYA CHEMICAL CO., LTD. (JP) | 2020-11-19 | — | — | US | disclosed |