SCHEMBL22007456

SCHEMBL22007456

c1ccc(N(c2ccc(-c3ccc(N(c4ccccc4)c4cccc(-n5nc6ccccc6n5)c4)cc3)cc2)c2cccc(-n3nc4ccccc4n3)c2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.52
HPGD P15428 4/20 0.52
ALDH1A1 P00352 8/20 0.41
NPC1 O15118 5/20 0.41
RAB9A P51151 5/20 0.41
MAPT P10636 4/20 0.41
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
STAT1 P42224 1/20 0.41
SMN1; SMN2 Q16637 4/20 0.37
CYP1A2 P05177 2/20 0.37
CYP2D6 P10635 2/20 0.37
CYP2C9 P11712 2/20 0.37
CYP2C19 P33261 2/20 0.37
TP53 P04637 2/20 0.37
HSD17B10 Q99714 2/20 0.37
GAA P10253 1/20 0.37
NFKB1 P19838 1/20 0.37
CASP1 P29466 1/20 0.37
CASP7 P55210 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22181970 1.00 KDM4E (0.52) KDM4EHPGDALDH1A1NPC1RAB9A
SCHEMBL30442802 0.98 KDM4E (0.50) KDM4EHPGDALDH1A1NPC1RAB9A
SCHEMBL22653496 0.98 KDM4E (0.50) KDM4EHPGDALDH1A1NPC1RAB9A
SCHEMBL30442871 0.89 KDM4E (0.40) KDM4EHPGDALDH1A1NPC1RAB9A
SCHEMBL22687364 0.89 KDM4E (0.40) KDM4EHPGDALDH1A1NPC1RAB9A
SCHEMBL22007083 0.88 NPC1 (0.53) KDM4EHPGDALDH1A1NPC1RAB9A
SCHEMBL22007073 0.88 NPC1 (0.53) KDM4EHPGDALDH1A1NPC1RAB9A
SCHEMBL22007066 0.88 NPC1 (0.53) KDM4EHPGDALDH1A1NPC1RAB9A
SCHEMBL22007580 0.87 KDM4E (0.59) KDM4EHPGDALDH1A1NPC1RAB9A
SCHEMBL20656694 0.87 KDM4E (0.59) KDM4EHPGDALDH1A1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230284515-A1 POLYCYCLIC AROMATIC DERIVATIVE COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT USING THE SAME SFC CO., LTD. (KR) 2023-09-07 US disclosed
US-20230284515-A1 POLYCYCLIC AROMATIC DERIVATIVE COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT USING THE SAME SFC CO., LTD. (KR) 2023-09-07 US disclosed
EP-3750971-B1 ORGANIC ELECTROLUMINESCENT DEVICE SFC CO LTD (KR) 2023-02-22 EP disclosed
US-20220149291-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT HODOGAYA CHEMICAL CO., LTD. (JP) 2022-05-12 US disclosed
US-20220102635-A1 ORGANIC LIGHT-EMITTING ELEMENT USING POLYCYCLIC AROMATIC DERIVATIVE COMPOUND SFC CO., LTD. (KR) 2022-03-31 US disclosed
US-11056653-B2 Organic electroluminescence device HODOGAYA CHEMICAL CO., LTD. (JP) 2021-07-06 US disclosed
US-20210167293-A1 POLYCYCLIC AROMATIC COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICES USING THE SAME SFC CO., LTD. (KR) 2021-06-03 US disclosed
EP-3660024-B1 POLYCYCLIC AROMATIC COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICES USING THE SAME SFC CO LTD (KR) 2021-05-05 EP disclosed
US-10981938-B2 Polycyclic aromatic compounds and organic electroluminescent devices using the same SFC CO., LTD. (KR) 2021-04-20 US disclosed
US-20200395553-A1 ORGANIC ELECTROLUMINESCENT DEVICE SFC CO., LTD. (KR) 2020-12-17 US disclosed
US-20200328353-A1 Organic Electroluminescence Device HODOGAYA CHEMICAL CO., LTD. (JP) 2020-10-15 US disclosed
US-20200172558-A1 POLYCYCLIC AROMATIC COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICES USING THE SAME SFC CO., LTD. (KR) 2020-06-04 US disclosed
US-20200161552-A1 INDOLOCARBAZOLE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT DEVICES USING THE SAME SFC CO., LTD. (KR) 2020-05-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200172558-A1 POLYCYCLIC AROMATIC COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICES USING THE SAME DDC, TYR, DDT KDM4E 1011/4885HPGD 2256/4885ALDH1A1 711/4885
US-20220102635-A1 ORGANIC LIGHT-EMITTING ELEMENT USING POLYCYCLIC AROMATIC DERIVATIVE COMPOUND TRPA1, TYR, ZKSCAN2 KDM4E 582/4885HPGD 3907/4885ALDH1A1 1979/4885
US-20230284515-A1 POLYCYCLIC AROMATIC DERIVATIVE COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT USING THE SAME ARNT, AHR, TYR KDM4E 812/4885HPGD 2734/4885ALDH1A1 605/4885
US-20210167293-A1 POLYCYCLIC AROMATIC COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICES USING THE SAME DDC, TYR, DDT KDM4E 1011/4885HPGD 2256/4885ALDH1A1 711/4885
US-10981938-B2 Polycyclic aromatic compounds and organic electroluminescent devices using the same DDC, TYR, DDT KDM4E 1011/4885HPGD 2256/4885ALDH1A1 711/4885
US-20200395553-A1 ORGANIC ELECTROLUMINESCENT DEVICE LEF1, AP2A2, CCNA1 KDM4E 3986/4885HPGD 3352/4885ALDH1A1 17/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.