⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7738807 | 0.86 | — | — | |
| SCHEMBL2583995 | 0.77 | — | — | |
| SCHEMBL8304495 | 0.76 | — | — | |
| SCHEMBL12245632 | 0.73 | — | — | |
| SCHEMBL23883673 | 0.73 | ALOX15 (0.31) | — | |
| SCHEMBL9839303 | 0.71 | — | — | |
| SCHEMBL23480262 | 0.71 | — | — | |
| SCHEMBL4115988 | 0.71 | USP2 (0.30) | — | |
| SCHEMBL23480261 | 0.70 | — | — | |
| SCHEMBL24615875 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109776509-B | N-substituted imidazole formate derivative and application thereof | 成都麻沸散医药科技有限公司 | 2023-07-07 | — | — | CN | disclosed |
| US-11434205-B2 | Substituted imidazole carboxylate derivatives and the use thereof | CHENGDU MFS PHARMA. CO., LTD. (CN) | 2022-09-06 | — | — | US | disclosed |
| EP-3747869-A1 | SUBSTITUTED IMIDAZOLE FORMATE DERIVATIVE AND USE THEREOF | CHENGDU MFS PHARMA. CO., LTD. (CN) | 2020-12-09 | — | — | EP | disclosed |
| US-20200369621-A1 | SUBSTITUTED IMIDAZOLECARBOXYLATE DERIVATIVES AND THE USE THEREOF | CHENGDU MFS PHARMA. CO., LTD. (CN) | 2020-11-26 | — | — | US | disclosed |
| CN-109776509-A | A kind of N- substituted imidazole formate ester derivative and application thereof | 成都安诺晨创医药科技有限公司 | 2019-05-21 | — | — | CN | disclosed |