SCHEMBL22688446

SCHEMBL22688446

Brc1ccc(-c2cccc3sc4c5ccccc5ccc4c23)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A1 P04798 6/20 0.40
CYP1B1 Q16678 6/20 0.40
CYP1A2 P05177 4/20 0.40
LIMK1 P53667 1/20 0.37
ALOX5 P09917 1/20 0.37
HDAC8 Q9BY41 1/20 0.35
HDAC6 Q9UBN7 1/20 0.35
CA12 O43570 2/20 0.35
CA1 P00915 2/20 0.35
CA2 P00918 2/20 0.35
CA9 Q16790 2/20 0.35
PLK4 O00444 1/20 0.35
AURKA O14965 1/20 0.35
JAK2 O60674 1/20 0.35
LCK P06239 1/20 0.35
CDK1 P06493 1/20 0.35
CSF1R P07333 1/20 0.35
LYN P07948 1/20 0.35
FGFR1 P11362 1/20 0.35
SRC P12931 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30020373 0.88 CYP1A1 (0.51) CYP1A1CYP1B1CYP1A2LIMK1ALOX5
SCHEMBL25790537 0.86 ALOX5 (0.46) CYP1A1CYP1B1CYP1A2LIMK1ALOX5
SCHEMBL24469323 0.84 CYP1A1 (0.46) CYP1A1CYP1B1CYP1A2LIMK1ALOX5
SCHEMBL17382927 0.84 ALOX5 (0.40) CYP1A1CYP1B1CYP1A2LIMK1ALOX5
SCHEMBL17383087 0.84 CYP1A1 (0.43) CYP1A1CYP1B1CYP1A2LIMK1ALOX5
SCHEMBL25460203 0.83 CYP1A1 (0.45) CYP1A1CYP1B1CYP1A2LIMK1ALOX5
SCHEMBL24469327 0.83 CYP1A1 (0.45) CYP1A1CYP1B1CYP1A2LIMK1ALOX5
SCHEMBL17382965 0.83 ALOX5 (0.40) CYP1A1CYP1B1CYP1A2LIMK1ALOX5
SCHEMBL17382912 0.83 CYP1A1 (0.40) CYP1A1CYP1B1CYP1A2ALOX5CA12
SCHEMBL17383094 0.82 CYP1A1 (0.42) CYP1A1CYP1B1CYP1A2LIMK1ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020231197-A1 ORGANIC ELECTRIC ELEMENT COMPRISING COMPOUND FOR ORGANIC ELECTRIC ELEMENT, AND ELECTRONIC DEVICE THEREOF 덕산네오룩스 주식회사 2020-11-19 WO disclosed