Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.50 |
| ▸ | RORC | P51449 | 3/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 12/20 | 0.36 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.36 |
| ▸ | KIT | P10721 | 1/20 | 0.36 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 4/20 | 0.34 |
| ▸ | NTRK3 | Q16288 | 3/20 | 0.34 |
| ▸ | NTRK2 | Q16620 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22688748 | 1.00 | PCSK9 (0.50) | PCSK9RORCIRAK4MAP3K7KIT | |
| SCHEMBL29422685 | 0.87 | NTRK1 (0.42) | NTRK1NTRK3NTRK2 | |
| SCHEMBL22688714 | 0.85 | NTRK1 (0.40) | NTRK1NTRK3NTRK2 | |
| SCHEMBL22688715 | 0.85 | NTRK1 (0.40) | NTRK1NTRK3NTRK2 | |
| SCHEMBL29422648 | 0.73 | PCSK9 (0.36) | PCSK9NTRK1NTRK3NTRK2 | |
| SCHEMBL22688739 | 0.73 | NTRK1 (0.46) | NTRK1NTRK3NTRK2 | |
| SCHEMBL22688740 | 0.73 | NTRK1 (0.46) | NTRK1NTRK3NTRK2 | |
| SCHEMBL29797171 | 0.72 | NTRK1 (0.42) | NTRK1NTRK3NTRK2 | |
| SCHEMBL29422756 | 0.72 | NTRK1 (0.40) | NTRK1NTRK3NTRK2 | |
| SCHEMBL22688769 | 0.72 | TRPA1 (0.33) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020233645-A1 | MACROLIDE DERIVATIVES, PREPARATION METHOD AND APPLICATION THEREOF | 浙江海正药业股份有限公司 (CN) | 2020-11-26 | — | — | WO | disclosed |