Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.37 |
| ▸ | PSMB11 | A5LHX3 | 6/20 | 0.36 |
| ▸ | PSMA7 | O14818 | 6/20 | 0.36 |
| ▸ | PSMB1 | P20618 | 6/20 | 0.36 |
| ▸ | PSMA1 | P25786 | 6/20 | 0.36 |
| ▸ | PSMA2 | P25787 | 6/20 | 0.36 |
| ▸ | PSMA3 | P25788 | 6/20 | 0.36 |
| ▸ | PSMA4 | P25789 | 6/20 | 0.36 |
| ▸ | PSMB8 | P28062 | 6/20 | 0.36 |
| ▸ | PSMB9 | P28065 | 6/20 | 0.36 |
| ▸ | PSMA5 | P28066 | 6/20 | 0.36 |
| ▸ | PSMB4 | P28070 | 6/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2270069 | 0.89 | PTPRC (0.50) | PTPRCALDH1A1MAPTMAPK1SMN1; SMN2 | |
| SCHEMBL2272438 | 0.86 | TP53 (0.40) | ALDH1A1MAPTMAPK1SMN1; SMN2KDM4E | |
| SCHEMBL2271537 | 0.85 | ALDH1A1 (0.46) | ALDH1A1MAPTMEN1POLBKMT2A | |
| SCHEMBL2268881 | 0.80 | PTPRC (0.47) | PTPRCALDH1A1MAPTMAPK1SMN1; SMN2 | |
| SCHEMBL2272381 | 0.80 | ACE2 (0.47) | ALDH1A1MAPTMAPK1SMN1; SMN2KDM4E | |
| SCHEMBL2274343 | 0.79 | ALDH1A1 (0.46) | ALDH1A1MAPTMAPK1SMN1; SMN2KDM4E | |
| SCHEMBL2274863 | 0.79 | ALDH1A1 (0.55) | ALDH1A1MAPTMAPK1SMN1; SMN2KDM4E | |
| SCHEMBL2268887 | 0.79 | PTPRC (0.42) | PTPRCCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL2274384 | 0.78 | MAPT (0.44) | ALDH1A1MAPTMAPK1SMN1; SMN2KDM4E | |
| SCHEMBL2270337 | 0.78 | HPGD (0.46) | ALDH1A1MAPTMAPK1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8530465-B2 | 1, 2-disubstituted amido-anthraquinone derivatives, preparation method and application thereof | NATIONAL DEFENSE MEDICAL CENTER (TW) | 2013-09-10 | — | — | US | disclosed |
| US-20130059862-A1 | Novel 1, 2-Disubstituted Amido-anthraquinone Derivatives, Preparation Method and application thereof | HUANG HSU-SHAN (TW) | 2013-03-07 | — | — | US | disclosed |
| US-8304415-B2 | 1, 2-disubstituted amido-anthraquinone derivatives, preparation method and application thereof | NATIONAL DEFENSE MEDICAL CENTER (TW) | 2012-11-06 | — | — | US | disclosed |
| US-20110207739-A1 | Novel 1, 2-Disubstituted Amido-anthraquinone Derivatives, Preparation Method and application thereof | NATIONAL DEFENSE MEDICAL CENTER (TW) | 2011-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110207739-A1 | Novel 1, 2-Disubstituted Amido-anthraquinone Derivatives, Preparation Method and application thereof | ANXA1, ANXA5, ANXA2 | PTPRC 3858/4885CHRM2 4873/4885CHRM4 4881/4885 |
| US-20130059862-A1 | Novel 1, 2-Disubstituted Amido-anthraquinone Derivatives, Preparation Method and application thereof | ANXA5, ANXA1, HCCS | PTPRC 3056/4885CHRM2 4857/4885CHRM4 4871/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.