Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 2/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 2/20 | 0.43 |
| ▸ | CD44 | P16070 | 1/20 | 0.43 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.41 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.41 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.41 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.41 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29805885 | 1.00 | NUDT1 (0.46) | NUDT1PARP1BCHECD44GRIA1 | |
| SCHEMBL9267430 | 0.92 | PARP1 (0.42) | NUDT1PARP1BCHECD44GRIA1 | |
| SCHEMBL126414 | 0.88 | PARP1 (0.56) | NUDT1PARP1BCHECD44GID4 | |
| SCHEMBL30826409 | 0.78 | NUDT1 (0.47) | NUDT1PARP1BCHEGRIA1GRIA2 | |
| SCHEMBL5757236 | 0.78 | NUDT1 (0.47) | NUDT1PARP1BCHEGRIA1GRIA2 | |
| SCHEMBL23564778 | 0.76 | GRIA1 (0.41) | NUDT1PARP1BCHEGRIA1GRIA2 | |
| SCHEMBL2260714 | 0.76 | GRIA1 (0.41) | NUDT1BCHEGRIA1GRIA2GRIA3 | |
| SCHEMBL8650202 | 0.76 | PARP10 (0.44) | NUDT1BCHEGRIA1GRIA2GRIA3 | |
| SCHEMBL17969115 | 0.76 | GRIA1 (0.41) | NUDT1PARP1BCHEGRIA1GRIA2 | |
| SCHEMBL6780467 | 0.76 | GRIA1 (0.45) | NUDT1PARP1BCHEGRIA1GRIA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1413286-B1 | Dyeing composition comprising at least one heterocyclic oxidation base and at least one substituted 2,3-diaminopyridine as a coupling agent | OREAL (FR) | 2009-04-22 | — | — | EP | claimed |
| WO-2007071688-A1 | COMPOSITION FOR DYEING KERATIN FIBRES WITH A TETRAAZAPENTAMETHINE CATIONIC DIRECT DYE, A PARTICULAR OXIDATION BASE AND A COUPLER | L'ORÉAL (FR) | 2007-06-28 | — | — | WO | claimed |
| EP-1413286-A1 | Dyeing composition comprising at least one heterocyclic oxidation base and at least one substituted 2,3-diaminopyridine as a coupling agent | L'OREAL (FR) | 2004-04-28 | — | — | EP | claimed |
| CN-112604706-B | Preparation method and application of Co@CN catalyst derived from nitrogen-containing super-crosslinked polymer | 荆楚理工学院 | 2023-11-10 | — | — | CN | disclosed |
| CN-114829344-A | Novel pyrimidine derivative and use thereof | 韩国化学研究院 | 2022-07-29 | — | — | CN | disclosed |
| WO-2021127047-A1 | COMBINATIONS | RECURIUM IP HOLDINGS, LLC (US) | 2021-06-24 | — | — | WO | disclosed |
| WO-2021127044-A1 | COMBINATIONS | RECURIUM IP HOLDINGS, LLC (US) | 2021-06-24 | — | — | WO | disclosed |
| WO-2020210320-A1 | SUBSTITUTED L,2-DIHYDRO-3H-PYRAZOLO[3,4-D]PYRIMIDIN-3-ONES | RECURIUM IP HOLDINGS, LLC (US) | 2020-10-15 | — | — | WO | disclosed |
| CN-109206435-B | Thieno [3,2-d ] pyrimidine compound and preparation method and medical application thereof | 中国医药研究开发中心有限公司 | 2020-09-08 | — | — | CN | disclosed |
| WO-2019173082-A1 | SUBSTITUTED L,2-DIHYDRO-3H-PYRAZOLO[3,4-D]PYRIMIDIN-3-ONES | Zeno Royalties & Milestones, LLC (US) | 2019-09-12 | — | — | WO | disclosed |
| CN-109206435-A | Thieno [3,2-d] pyrimidines and preparation method thereof and medical usage | 中国医药研究开发中心有限公司 | 2019-01-15 | — | — | CN | disclosed |
| EP-2182914-A2 | COMPOSITION OXIDATION COLOURING OF KERATINIC FIBRES, CONTAINING A CATIONIC CELLULOSE ETHER, A METASILICATE AND OXIDATION DYES, METHOD FOR OXIDATION COLOURING AND USES THEREOF | L'Oreal (FR) | 2010-05-12 | — | — | EP | disclosed |
| EP-2175830-A2 | COMPOSITION FOR OXIDATION DYEING KERATIN FIBRES COMPRISING A CATIONIC CELLULOSE ETHER, A WEAKLY OXYETHYLENATED SORBITAN FATTY ACID ESTER AND OXIDATION DYES | L'Oreal (FR) | 2010-04-21 | — | — | EP | disclosed |
| EP-1413286-B1 | Dyeing composition comprising at least one heterocyclic oxidation base and at least one substituted 2,3-diaminopyridine as a coupling agent | OREAL (FR) | 2009-04-22 | — | — | EP | disclosed |
| WO-2009019383-A2 | COMPOSITION OXIDATION COLOURING OF KERATINIC FIBRES, CONTAINING A CATIONIC CELLULOSE ETHER, A METASILICATE AND OXIDATION DYES, METHOD FOR OXIDATION COLOURING AND USES THEREOF | L'OREAL (FR) | 2009-02-12 | — | — | WO | disclosed |
| WO-2009016061-A2 | COMPOSITION FOR OXIDATION DYEING KERATIN FIBRES COMPRISING A CATIONIC CELLULOSE ETHER, A WEAKLY OXYETHYLENATED SORBITAN FATTY ACID ESTER AND OXIDATION DYES | L'OREAL (FR) | 2009-02-05 | — | — | WO | disclosed |
| WO-2007071688-A1 | COMPOSITION FOR DYEING KERATIN FIBRES WITH A TETRAAZAPENTAMETHINE CATIONIC DIRECT DYE, A PARTICULAR OXIDATION BASE AND A COUPLER | L'ORÉAL (FR) | 2007-06-28 | — | — | WO | disclosed |
| WO-2006028957-A1 | 4-SUBSTITUTED 4, 6-DIALKOXY-CINNOLINE DERIVATIVES AS PHOSPODIESTERASE 10 INHIBITORS FOR THE TREATMENT OF PSYCHIATRIC OR NEUROLOGICAL SYNDROMS | MEMORY PHARMACEUTICALS CORPORATION (US) | 2006-03-16 | — | — | WO | disclosed |
| EP-1459732-A1 | Dye composition comprising at least one heterocyclic oxidation base and at least one 2,3,5-triaminopyridine as coupler | L'OREAL (FR) | 2004-09-22 | — | — | EP | disclosed |
| EP-1413286-A1 | Dyeing composition comprising at least one heterocyclic oxidation base and at least one substituted 2,3-diaminopyridine as a coupling agent | L'OREAL (FR) | 2004-04-28 | — | — | EP | disclosed |