SCHEMBL2269105

SCHEMBL2269105

CCCC[Si](Cl)(CCCC)C(C)C

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.33
TDP1 Q9NUW8 1/20 0.32
LMNA P02545 1/20 0.32
OPRM1 P35372 1/20 0.31
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2273603 0.95 TSHR (0.31) TSHR
SCHEMBL30173776 0.83 TSHR (0.32) TSHRTDP1LMNAOPRM1THRB
SCHEMBL2275292 0.79
SCHEMBL4644804 0.78 TSHR (0.32) TSHRTDP1LMNAOPRM1THRB
SCHEMBL2102289 0.78 TSHR (0.32) TSHRTDP1LMNAOPRM1THRB
SCHEMBL2271368 0.72
SCHEMBL15914659 0.71 TSHR (0.35) TSHRLMNAOPRM1THRB
SCHEMBL17735524 0.71 TSHR (0.35) TSHRLMNAOPRM1THRB
SCHEMBL28404239 0.70 TSHR (0.39) TSHR
SCHEMBL2101068 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8404584-B2 Method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2013-03-26 US disclosed
US-20110207319-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2011-08-25 US disclosed