Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | TLR2 | O60603 | 2/20 | 0.48 |
| ▸ | MDM4 | O15151 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MDM2 | Q00987 | 4/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29423637 | 1.00 | KMT2A (0.53) | KMT2ATLR2MDM4TP53MDM2 | |
| SCHEMBL29401148 | 0.92 | KMT2A (0.55) | KMT2ATLR2MDM4TP53MDM2 | |
| SCHEMBL29569815 | 0.92 | KMT2A (0.55) | KMT2ATLR2MDM4TP53MDM2 | |
| SCHEMBL29850382 | 0.92 | KMT2A (0.55) | KMT2ATLR2MDM4TP53MDM2 | |
| SCHEMBL13401519 | 0.92 | KMT2A (0.55) | KMT2ATLR2MDM4TP53MDM2 | |
| SCHEMBL25356641 | 0.92 | KMT2A (0.55) | KMT2ATLR2MDM4TP53MDM2 | |
| SCHEMBL119468 | 0.92 | KMT2A (0.55) | KMT2ATLR2MDM4TP53MDM2 | |
| SCHEMBL31647336 | 0.92 | KMT2A (0.55) | KMT2ATLR2MDM4TP53MDM2 | |
| SCHEMBL29362229 | 0.92 | KMT2A (0.55) | KMT2ATLR2MDM4TP53MDM2 | |
| SCHEMBL14546586 | 0.91 | KMT2A (0.51) | KMT2ATLR2MDM4TP53MDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023223097-A1 | ANTIBODY DRUG CONJUGATES | NOVARTIS AG (CH) | 2023-11-23 | — | — | WO | disclosed |
| WO-2020236841-A2 | ANTIBODY DRUG CONJUGATES HAVING LINKERS COMPRISING HYDROPHILIC GROUPS | NOVARTIS AG (CH) | 2020-11-26 | — | — | WO | disclosed |